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Kim, Hyun Uk (김현욱)
부교수, (생명화학공학과)
Research Area
Systems biology, Systems medicine, Metabolic engineering
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    NO Title, Author(s) (Publication Title, Volume Issue, Page, Issue Date)
    Heterologous overproduction of oviedomycin by refactoring biosynthetic gene cluster and metabolic engineering of host strain Streptomyces coelicolor

    Gu, Boncheol; Kim, Duck Gyun; Kim, Do-Kyung; et al, MICROBIAL CELL FACTORIES, v.22, no.1, 2023-12

    Genome-wide identification of overexpression and downregulation gene targets based on the sum of covariances of the outgoing reaction fluxes

    Kim, Won Jun; Lee, Youngjoon; Kim, Hyun Uk; et al, CELL SYSTEMS, v.14, no.11, pp.990 - 1001, 2023-11

    Artificial intelligence for natural product drug discovery

    Mullowney, Michael W.; Duncan, Katherine R.; Elsayed, Somayah S.; et al, NATURE REVIEWS DRUG DISCOVERY, v.22, no.11, pp.895 - 916, 2023-09

    Modification of a PES microfiltration membrane to enhance sterile filtration by inhibiting protein adsorption

    Yun, Kang Hee; Sharma, Komal; Kim, Hyun Uk; et al, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.123, pp.311 - 319, 2023-07

    Factors affecting the competitiveness of bacterial fermentation

    Lee, Jongan; Kim, Hyun Uk; Na, Jeong-Geol; et al, TRENDS IN BIOTECHNOLOGY, v.41, no.6, pp.798 - 816, 2023-06

    A contribution of metabolic engineering to addressing medical problems: Metabolic flux analysis

    Lee, GaRyoung; Lee, Sang Mi; Kim, Hyun Uk, METABOLIC ENGINEERING, v.77, pp.283 - 293, 2023-05

    Targeted and high-throughput gene knockdown in diverse bacteria using synthetic sRNAs

    Cho, Jae Sung; Yang, Dongsoo; Prabowo, Cindy Pricilia Surya; et al, NATURE COMMUNICATIONS, v.14, no.1, 2023-04

    Computational prediction of interactions between Paxlovid and prescription drugs

    Kim, Yeji; Ryu, Jae Yong; Kim, Hyun Uk; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.120, no.12, 2023-03

    Deep learning enables accurate analysis of images generated from droplet-based digital polymerase chain reaction (dPCR)

    Song, Younseong; Lim, Seongjin; Kim, Yong Tae; et al, SENSORS AND ACTUATORS B-CHEMICAL, v.379, 2023-03

    Proteomic analysis for the effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on Alzheimer's disease in a mouse model

    Kim, Sujin; Nam, Yunkwon; Kim, Min-jeong; et al, JOURNAL OF GINSENG RESEARCH, v.47, no.2, pp.302 - 310, 2023-03

    Recent development of machine learning models for the prediction of drug-drug interactions

    Hong, Eujin; Jeon, Junhyeok; Kim, Hyun Uk, KOREAN JOURNAL OF CHEMICAL ENGINEERING, v.40, no.2, pp.276 - 285, 2023-02

    Predicting the effects of cultivation condition on gene regulation in Escherichia coli by using deep learning

    Kwon, Mun Su; Adidjaja, Joshua Julio; Kim, Hyun Uk, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, v.21, pp.2613 - 2620, 2023

    Systems metabolic engineering of Corynebacterium glutamicum for the efficient production of 13-alanine

    Ghiffary, Mohammad Rifqi; Prabowo, Cindy Pricilia Surya; Adidjaja, Joshua Julio; et al, METABOLIC ENGINEERING, v.74, pp.121 - 129, 2022-11

    Systems metabolic engineering of Streptomyces venezuelae for the enhanced production of pikromycin

    Cho, Min Kyung; Lee, Byung Tae; Kim, Hyun Uk; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.119, no.8, pp.2250 - 2260, 2022-08

    Comparative genomic analysis of Streptomyces rapamycinicus NRRL 5491 and its mutant overproducing rapamycin

    Jo, Hee-Geun; Adidjaja, Joshua Julio; Kim, Do-Kyung; et al, SCIENTIFIC REPORTS, v.12, no.1, pp.10302, 2022-06

    Machine learning-guided evaluation of extraction and simulation methods for cancer patient-specific metabolic models

    Lee, Sang Mi; Lee, GaRyoung; Kim, Hyun Uk, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, v.20, pp.3041 - 3052, 2022-06

    Efficient Production of Naringin Acetate with Different Acyl Donors via Enzymatic Transesterification by Lipases

    Baek, Yesol; Lee, Seungmee; Son, Jemin; et al, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v.19, no.5, pp.2972, 2022-03

    Development of computational models using omics data for the identification of effective cancer metabolic biomarkers

    Lee, Sang Mi; Kim, Hyun Uk, MOLECULAR OMICS, v.17, no.6, pp.881 - 893, 2021-12

    Predicting Dynamic Clinical Outcomes of the Chemotherapy for Canine Lymphoma Patients Using a Machine Learning Model

    Koo, Jamin; Choi, Kyucheol; Lee, Peter; et al, VETERINARY SCIENCES, v.8, no.12, pp.8120301, 2021-12

    Predicting biochemical and physiological effects of natural products from molecular structures using machine learning

    Jeon, Junhyeok; Kang, Seongmo; Kim, Hyun Uk, NATURAL PRODUCT REPORTS, v.38, no.11, pp.1954 - 1966, 2021-11

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