Researcher Page

Kim, Chan Hyuk (김찬혁)
부교수, (생명과학과)
Research Area
Immunotherapy, Antibody Engineering, Cell Therapy
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    NO Title, Author(s) (Publication Title, Volume Issue, Page, Issue Date)
    Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus

    Lah, Sangjoon; Kim, Segi; Kang, In; et al, JOURNAL FOR IMMUNOTHERAPY OF CANCER, v.11, no.4, 2023-04

    Adolescent Parvalbumin Expression in the Left Orbitofrontal Cortex in Female Mice

    Jeon, Yi-Seon; Jeong, Daun; Kweon, Hanseul; et al, JOURNAL OF NEUROSCIENCE, v.43, no.9, pp.1555 - 1571, 2023-03

    Reprogramming of IL-12 secretion in the PDCD1 locus improves the anti-tumor activity of NY-ESO-1 TCR-T cells

    Kim, Segi; Park, Cho I.; Lee, Sunhwa; et al, FRONTIERS IN IMMUNOLOGY, v.14, 2023-01

    Toward inflammation-free therapeutics in Alzheimer's disease

    Kim, Chan Hyukresearcher; Chung, Won-Sukresearcher, NATURE MEDICINE, v.28, no.9, pp.1765 - 1766, 2022-09

    Anti-inflammatory clearance of amyloid-beta by a chimeric Gas6 fusion protein

    Jung, Hyuncheol; Lee, Se Young; Lim, Seongjoon; et al, NATURE MEDICINE, v.28, no.9, pp.1802 - 1812, 2022-09

    A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis

    Lee, Eunbeol; Jung, Yeon-Joo; Park, Yu Rim; et al, NATURE AGING, v.2, no.8, pp.726 - 741, 2022-08

    CAR T Cell Immunotherapy Beyond Haematological Malignancy

    Hupperetz, Cedric; Lah, Sangjoon; Kim, Hyojin; et al, IMMUNE NETWORK, v.22, no.1, pp.1 - 19, 2022-02

    PD-1 and TIGIT downregulation distinctly affect the effector and early memory phenotypes of CD19-targeting CAR T cells

    Lee, Young-Ho; Lee, Hyeong Ji; Kim, Hyung Cheol; et al, MOLECULAR THERAPY, v.30, no.2, pp.579 - 592, 2022-02

    A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand

    Lee, Sung Chang; Ma, Jennifer S. Y.; Kim, Min Soo; et al, SCIENCE ADVANCES, v.7, no.33, 2021-08

    Genome editing of immune cells using CRISPR/Cas9

    Kim, Segi; Hupperetz, Cedric; Lim, Seongjoon; et al, BMB REPORTS, v.54, no.1, pp.59 - 69, 2021-01

    Evolution of chimeric antigen receptor (CAR) T cell therapy: current status and future perspectives

    Lee, Young-Ho; Kim, Chan Hyukresearcher, ARCHIVES OF PHARMACAL RESEARCH, v.42, no.7, pp.607 - 616, 2019-07

    Soluble c receptor attenuates anti-tumor responses of CD8(+) T cells in T cell immunotherapy

    Kim, Geona; Hwang, Hyunju; Jo, Yuna; et al, INTERNATIONAL JOURNAL OF CANCER, v.143, no.5, pp.1212 - 1223, 2018-09

    Engineering Bifunctional Antibodies with Constant Region Fusion Architectures

    Du, Juanjuan; Cao, Yu; Liu, Yan; et al, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.139, no.51, pp.18607 - 18615, 2017-12

    Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia

    Laborda, Eduardo; Mazagova, Magdalena; Shao, Sida; et al, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.18, no.11, pp.2259 - 2266, 2017-10

    Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding

    Lee, Taehyung C.; Kang, Minjin; Kim, Chan Hyukresearcher; et al, ChemBioChem, v.17, no.11, pp.981 - 984, 2016-06

    Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

    Cao, Yu; Rodgers, David T; Du, Juanjuan; et al, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.55, no.26, pp.7520 - 7524, 2016-06

    Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies

    Rodgers, David T.; Mazagova, Magdalena; Hampton, Eric N.; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.113, no.4, pp.459 - 468, 2016-01

    Versatile strategy for controlling the specificity and activity of engineered T cells

    Ma, Jennifer S. Y.; Kim, Ji Young; Kazane, Stephanie A.; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.113, no.4, pp.450 - 458, 2016-01

    Multiformat T-Cell-Engaging Bispecific Antibodies Targeting Human Breast Cancers

    Cao, Yu; Axup, Jun Y.; Ma, Jennifer S. Y.; et al, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.54, no.24, pp.7022 - 7027, 2015-06

    An Anti-B Cell Maturation Antigen Bispecific Antibody for Multiple Myeloma

    Ramadoss, Nitya S.; Schulman, Andrew D.; Choi, Sei-hyun; et al, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.16, pp.5288 - 5291, 2015-04

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