DSpace at KOASAS
College of Natural Sciences(자연과학대학)Dept. of Chemistry(화학과)CH-Journal Papers(저널논문)

Synthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors

Cited 16 time in webofscience Cited 0 time in scopus
  • Hit : 491
  • Download : 0
Export
DC FieldValueLanguage
dc.contributor.authorLee, Ki-Hoko
dc.contributor.authorPark, Chun-Eungko
dc.contributor.authorMin, Kyung-Hyunko
dc.contributor.authorShin, Yong-Jeko
dc.contributor.authorChung, Coo-Minko
dc.contributor.authorKim, Hui-Hoko
dc.contributor.authorYoon, Hae-Jeoungko
dc.contributor.authorWon-Kimko
dc.contributor.authorRyu, Eun-Juko
dc.contributor.authorShin, Yu-Jinko
dc.contributor.authorNam, Hyun-Sikko
dc.contributor.authorCho, Jeong-Wooko
dc.contributor.authorLee, Hee Yoonko
dc.date.accessioned2013-03-11T06:17:07Z-
dc.date.available2013-03-11T06:17:07Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2010-09-
dc.identifier.citationBIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.20, no.18, pp.5567 - 5571-
dc.identifier.issn0960-894X-
dc.identifier.urihttp://hdl.handle.net/10203/98489-
dc.description.abstractA series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity. (C) 2010 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectTAIL SUSPENSION TEST-
dc.subjectMARBLE-BURYING BEHAVIOR-
dc.subjectSEROTONIN REUPTAKE-
dc.subjectANTIDEPRESSANT-
dc.subjectMICE-
dc.subjectBUPROPION-
dc.subjectDOPAMINE-
dc.subjectMODEL-
dc.subjectCOMBINATION-
dc.subjectDISORDER-
dc.titleSynthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors-
dc.typeArticle-
dc.identifier.wosid000281252700045-
dc.identifier.scopusid2-s2.0-77956169846-
dc.type.rimsART-
dc.citation.volume20-
dc.citation.issue18-
dc.citation.beginningpage5567-
dc.citation.endingpage5571-
dc.citation.publicationnameBIOORGANIC MEDICINAL CHEMISTRY LETTERS-
dc.identifier.doi10.1016/j.bmcl.2010.07.021-
dc.contributor.localauthorLee, Hee Yoon-
dc.contributor.nonIdAuthorPark, Chun-Eung-
dc.contributor.nonIdAuthorMin, Kyung-Hyun-
dc.contributor.nonIdAuthorShin, Yong-Je-
dc.contributor.nonIdAuthorChung, Coo-Min-
dc.contributor.nonIdAuthorKim, Hui-Ho-
dc.contributor.nonIdAuthorYoon, Hae-Jeoung-
dc.contributor.nonIdAuthorWon-Kim-
dc.contributor.nonIdAuthorRyu, Eun-Ju-
dc.contributor.nonIdAuthorShin, Yu-Jin-
dc.contributor.nonIdAuthorNam, Hyun-Sik-
dc.contributor.nonIdAuthorCho, Jeong-Woo-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorDepression-
dc.subject.keywordAuthorAntidepressant-
dc.subject.keywordAuthorSerotonin-
dc.subject.keywordAuthorNorepinephrine-
dc.subject.keywordAuthorDopamine-
dc.subject.keywordAuthorReuptake-
dc.subject.keywordAuthorInhibitor-
dc.subject.keywordPlusTAIL SUSPENSION TEST-
dc.subject.keywordPlusMARBLE-BURYING BEHAVIOR-
dc.subject.keywordPlusSEROTONIN REUPTAKE-
dc.subject.keywordPlusANTIDEPRESSANT-
dc.subject.keywordPlusMICE-
dc.subject.keywordPlusBUPROPION-
dc.subject.keywordPlusDOPAMINE-
dc.subject.keywordPlusMODEL-
dc.subject.keywordPlusCOMBINATION-
dc.subject.keywordPlusDISORDER-
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 16 items in WoS Click to see citing articles in records_button

Display Simple Item Record

qr_code

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


rss_1.0 rss_2.0 atom_1.0