Sensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry

Cited 3 time in webofscience Cited 0 time in scopus
  • Hit : 343
  • Download : 0
DC FieldValueLanguage
dc.contributor.authorAhn, Jang-Hyukko
dc.contributor.authorJeong, Young-Suko
dc.contributor.authorLee, Tae-Geolko
dc.contributor.authorKim, Young-Pilko
dc.contributor.authorKim, Hak-Sungko
dc.date.accessioned2013-03-11T04:28:06Z-
dc.date.available2013-03-11T04:28:06Z-
dc.date.created2012-04-20-
dc.date.created2012-04-20-
dc.date.issued2012-03-
dc.identifier.citationBIOCHIP JOURNAL, v.6, no.1, pp.34 - 40-
dc.identifier.issn1976-0280-
dc.identifier.urihttp://hdl.handle.net/10203/98248-
dc.description.abstractA rapid and reliable analysis of toxins is prerequisite for food control and human healthcare. Here we demonstrate a simple and multiplexed assay of aflatoxins using time-of-flight secondary ion mass spectrometry (TOF-SIMS). By simply adsorbing either a single analyte or mixed ones onto a gold substrate, the corresponding secondary molecular ions ([M+H](+)) were clearly observed in a single mass spectrum. As a result of concentration-dependent peak intensity, quantitative and multiplexed analysis of different aflatoxin analogs from corns was accomplished with immunoaffinity column and TOF-SIMS analysis, which showed a good correlation with HPLC data. The detection sensitivity was estimated to be as low as 10 ng mL(-1) This approach presented here will find a wide application to detection of low-levels of toxins in a rapid and multiplexed way.-
dc.languageEnglish-
dc.publisherKOREAN BIOCHIP SOCIETY-KBCS-
dc.subjectSELF-ASSEMBLED MONOLAYERS-
dc.subjectTOF-SIMS-
dc.subjectQUANTITATIVE-ANALYSIS-
dc.subjectSURFACE-ANALYSIS-
dc.subjectB-1-
dc.subjectPROTEIN-
dc.subjectCOLUMN-
dc.subjectELISA-
dc.subjectHPLC-
dc.subjectNANOPARTICLES-
dc.titleSensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry-
dc.typeArticle-
dc.identifier.wosid000301684500005-
dc.identifier.scopusid2-s2.0-84863340678-
dc.type.rimsART-
dc.citation.volume6-
dc.citation.issue1-
dc.citation.beginningpage34-
dc.citation.endingpage40-
dc.citation.publicationnameBIOCHIP JOURNAL-
dc.identifier.doi10.1007/s13206-012-6105-8-
dc.contributor.localauthorKim, Hak-Sung-
dc.contributor.nonIdAuthorAhn, Jang-Hyuk-
dc.contributor.nonIdAuthorLee, Tae-Geol-
dc.contributor.nonIdAuthorKim, Young-Pil-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorAflatoxin-
dc.subject.keywordAuthorTOF-SIMS-
dc.subject.keywordAuthorQuantification-
dc.subject.keywordAuthorMultiplexed analysis-
dc.subject.keywordPlusSELF-ASSEMBLED MONOLAYERS-
dc.subject.keywordPlusTOF-SIMS-
dc.subject.keywordPlusQUANTITATIVE-ANALYSIS-
dc.subject.keywordPlusSURFACE-ANALYSIS-
dc.subject.keywordPlusB-1-
dc.subject.keywordPlusPROTEIN-
dc.subject.keywordPlusCOLUMN-
dc.subject.keywordPlusELISA-
dc.subject.keywordPlusHPLC-
dc.subject.keywordPlusNANOPARTICLES-
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 3 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0