DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mok, Hyejung | ko |
dc.contributor.author | Park, Tae Gwan | ko |
dc.date.accessioned | 2013-03-09T15:58:52Z | - |
dc.date.available | 2013-03-09T15:58:52Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2009-08 | - |
dc.identifier.citation | MACROMOLECULAR BIOSCIENCE, v.9, no.8, pp.731 - 743 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | http://hdl.handle.net/10203/96802 | - |
dc.description.abstract | Cationic polymers have been chemically modified with a variety of targeting molecules such as peptides, proteins, antibodies, sugars and vitamins for targeted delivery of nucleic acid drugs to specific cells. Stimuli-sensitive polymers exhibiting different size, charge and conformation in response to physiological signals from specific cells have also been utilized for targeted delivery. To achieve target-specific delivery of nucleic acids, conjugation chemistry is critical to produce nanosized polyplexes tethered with cell-re ligands for facile cellular uptake via a mediated endocytic pathway. In this review, strategies of functional cationic polymers with various targeting ligands are presented. | - |
dc.language | English | - |
dc.publisher | Wiley-Blackwell | - |
dc.subject | POLYELECTROLYTE COMPLEX MICELLES | - |
dc.subject | EPIDERMAL-GROWTH-FACTOR | - |
dc.subject | MEDIATED GENE DELIVERY | - |
dc.subject | PLASMID DNA DELIVERY | - |
dc.subject | FOLATE RECEPTOR | - |
dc.subject | SIRNA DELIVERY | - |
dc.subject | IN-VITRO | - |
dc.subject | POLY(BETA-AMINO ESTER)S | - |
dc.subject | INTRACELLULAR DELIVERY | - |
dc.subject | CYCLIC-PEPTIDES | - |
dc.title | Functional Polymers for Targeted Delivery of Nucleic Acid Drugs | - |
dc.type | Article | - |
dc.identifier.wosid | 000269290400001 | - |
dc.identifier.scopusid | 2-s2.0-70049099303 | - |
dc.type.rims | ART | - |
dc.citation.volume | 9 | - |
dc.citation.issue | 8 | - |
dc.citation.beginningpage | 731 | - |
dc.citation.endingpage | 743 | - |
dc.citation.publicationname | MACROMOLECULAR BIOSCIENCE | - |
dc.identifier.doi | 10.1002/mabi.200900044 | - |
dc.contributor.localauthor | Park, Tae Gwan | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | bioengineering | - |
dc.subject.keywordAuthor | conjugated polymers | - |
dc.subject.keywordAuthor | drug delivery systems | - |
dc.subject.keywordAuthor | functionalization of polymers | - |
dc.subject.keywordAuthor | structure-property relations | - |
dc.subject.keywordPlus | POLYELECTROLYTE COMPLEX MICELLES | - |
dc.subject.keywordPlus | EPIDERMAL-GROWTH-FACTOR | - |
dc.subject.keywordPlus | MEDIATED GENE DELIVERY | - |
dc.subject.keywordPlus | PLASMID DNA DELIVERY | - |
dc.subject.keywordPlus | FOLATE RECEPTOR | - |
dc.subject.keywordPlus | SIRNA DELIVERY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | POLY(BETA-AMINO ESTER)S | - |
dc.subject.keywordPlus | INTRACELLULAR DELIVERY | - |
dc.subject.keywordPlus | CYCLIC-PEPTIDES | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.