Antitumor activity of methylan polysaccharide derivatives

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dc.contributor.authorPriyadharshini Ramachandranko
dc.contributor.authorMarimuthu Jeyako
dc.contributor.authorHee-Jung Moonko
dc.contributor.authorKyoung-Mi Leeko
dc.contributor.authorIn-Won Kimko
dc.contributor.authorKim, Jung Hoeko
dc.contributor.authorJung-Kul Leeko
dc.date.accessioned2013-03-09T06:22:59Z-
dc.date.available2013-03-09T06:22:59Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2010-07-
dc.identifier.citationBIOTECHNOLOGY LETTERS, v.32, pp.891 - 895-
dc.identifier.issn0141-5492-
dc.identifier.urihttp://hdl.handle.net/10203/95580-
dc.description.abstractMethylan polysaccharide derivatives were prepared by dialkylaminoalkylation and reductive amination followed by quaternization. Their antitumor activity was investigated and a relationship between structure and activity is suggested. For quaternized DEAE-methylan at only 75 mu g ml(-1), tumor cell proliferation was suppressed by 58-84% in three cell lines tested in the order Colo < Hela < HepG2.-
dc.languageEnglish-
dc.publisherSPRINGER-
dc.subjectMEDICINAL MUSHROOMS-
dc.subjectCAPACITY-
dc.titleAntitumor activity of methylan polysaccharide derivatives-
dc.typeArticle-
dc.identifier.wosid000278898100002-
dc.identifier.scopusid2-s2.0-77953872427-
dc.type.rimsART-
dc.citation.volume32-
dc.citation.beginningpage891-
dc.citation.endingpage895-
dc.citation.publicationnameBIOTECHNOLOGY LETTERS-
dc.identifier.doi10.1007/s10529-010-0246-4-
dc.contributor.localauthorKim, Jung Hoe-
dc.contributor.nonIdAuthorPriyadharshini Ramachandran-
dc.contributor.nonIdAuthorMarimuthu Jeya-
dc.contributor.nonIdAuthorHee-Jung Moon-
dc.contributor.nonIdAuthorKyoung-Mi Lee-
dc.contributor.nonIdAuthorIn-Won Kim-
dc.contributor.nonIdAuthorJung-Kul Lee-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorAmination-
dc.subject.keywordAuthorAntitumor-
dc.subject.keywordAuthorMethylan-
dc.subject.keywordAuthorPolysaccharide-
dc.subject.keywordPlusMEDICINAL MUSHROOMS-
dc.subject.keywordPlusCAPACITY-
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