Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery

Cited 839 time in webofscience Cited 0 time in scopus
  • Hit : 375
  • Download : 0
DC FieldValueLanguage
dc.contributor.authorYoo, Hyuk Sangko
dc.contributor.authorKim, Taek Gyoungko
dc.contributor.authorPark, Tae Gwanko
dc.date.accessioned2013-03-09T03:33:45Z-
dc.date.available2013-03-09T03:33:45Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2009-10-
dc.identifier.citationADVANCED DRUG DELIVERY REVIEWS, v.61, no.12, pp.1033 - 1042-
dc.identifier.issn0169-409X-
dc.identifier.urihttp://hdl.handle.net/10203/95256-
dc.description.abstractElectrospun nanofibers with a high surface area to volume ratio have received much attention because of their potential applications for biomedical devices, tissue engineering scaffolds, and drug delivery carriers. In order to develop electrospun nanofibers as useful nanobiomaterials, surfaces of electrospun nanofibers have been chemically functionalized for achieving sustained delivery through physical adsorption of diverse bioactive molecules. Surface modification of nanofibers includes plasma treatment, wet chemical method, surface graft polymerization, and co-electrospinning of surface active agents and polymers. A variety of bioactive molecules including anti-cancer drugs, enzymes, cytokines, and polysaccharides were entrapped within the interior or physically immobilized on the surface for controlled drug delivery. Surfaces of electrospun nanofibers were also chemically modified with immobilizing cell specific bioactive ligands to enhance cell adhesion, proliferation, and differentiation by mimicking morphology and biological functions of extracellular matrix. This review summarizes surface modification strategies of electrospun polymeric nanofibers for controlled drug delivery and tissue engineering. (c) 2009 Elsevier B.V. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE BV-
dc.subjectHEMATOPOIETIC STEM/PROGENITOR CELLS-
dc.subjectMESENCHYMAL STEM-CELLS-
dc.subjectPLASMA TREATMENT-
dc.subjectCONTROLLED-RELEASE-
dc.subjectPOLYELECTROLYTE MULTILAYERS-
dc.subjectPOLYMERIC NANOFIBERS-
dc.subjectGRAFT-POLYMERIZATION-
dc.subjectENDOTHELIAL-CELLS-
dc.subjectGROWTH-FACTOR-
dc.subjectIN-VITRO-
dc.titleSurface-functionalized electrospun nanofibers for tissue engineering and drug delivery-
dc.typeArticle-
dc.identifier.wosid000271395700005-
dc.identifier.scopusid2-s2.0-70349792411-
dc.type.rimsART-
dc.citation.volume61-
dc.citation.issue12-
dc.citation.beginningpage1033-
dc.citation.endingpage1042-
dc.citation.publicationnameADVANCED DRUG DELIVERY REVIEWS-
dc.identifier.doi10.1016/j.addr.2009.07.007-
dc.contributor.localauthorPark, Tae Gwan-
dc.contributor.nonIdAuthorYoo, Hyuk Sang-
dc.contributor.nonIdAuthorKim, Taek Gyoung-
dc.type.journalArticleReview-
dc.subject.keywordAuthorSurface-
dc.subject.keywordAuthorModification-
dc.subject.keywordAuthorElectrospinning-
dc.subject.keywordAuthorNanofiber-
dc.subject.keywordAuthorImmobilization-
dc.subject.keywordAuthorDrug delivery-
dc.subject.keywordAuthorTissue engineering-
dc.subject.keywordPlusHEMATOPOIETIC STEM/PROGENITOR CELLS-
dc.subject.keywordPlusMESENCHYMAL STEM-CELLS-
dc.subject.keywordPlusPLASMA TREATMENT-
dc.subject.keywordPlusCONTROLLED-RELEASE-
dc.subject.keywordPlusPOLYELECTROLYTE MULTILAYERS-
dc.subject.keywordPlusPOLYMERIC NANOFIBERS-
dc.subject.keywordPlusGRAFT-POLYMERIZATION-
dc.subject.keywordPlusENDOTHELIAL-CELLS-
dc.subject.keywordPlusGROWTH-FACTOR-
dc.subject.keywordPlusIN-VITRO-
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 839 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0