Growth Factors and Signaling Pathways in the Chondrogenic Differentiation of Mesenchymal Stem Cells

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Mesenchymal stem cells (MSCs) are multipotent progenitor cells that can differentiate into the several lineages. MSC has drawn an enormous attention because of the potential for use in tissue engineering and regenerative medicine. Several growth factors and signaling mechanisms strongly influence chondrogenic differentiation of MSCs. In this review, we summarized the roles of these growth factors and signaling mechanisms involved in chondrogenic differentiation of MSCs.
Publisher
KOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOC
Issue Date
2011-06
Language
English
Article Type
Article
Keywords

TGF-BETA; CHONDROCYTE DIFFERENTIATION; ARTICULAR-CARTILAGE; INDIAN-HEDGEHOG; MESODERM INDUCTION; BONE-DEVELOPMENT; GENE-EXPRESSION; STROMAL CELLS; MAP KINASE; RECEPTOR

Citation

TISSUE ENGINEERING AND REGENERATIVE MEDICINE, v.8, no.3, pp.292 - 299

ISSN
1738-2696
URI
http://hdl.handle.net/10203/94999
Appears in Collection
CH-Journal Papers(저널논문)
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