In this paper a new class of polyphase sequences for CDMA systems and its generation method are suggested, and the correlation properties of the sequence are investigated. The performance of the sequence in quasi-synchronous CDMA (QS-CDMA) systems is investigated under frequency-selective, time-nonselective. slow Nakagami fading channel with additive white Gaussian noise (AWGN), It is shown that the performance of the QS-CDMA systems using the suggested sequence is independent of the number of users and is much better than that using the PN sequence.