pH-Responsive mechanised nanoparticles gated by semirotaxanes

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A [2] pseudorotaxane-based mechanised nanoparticle system, which operates within an aqueous acidic environment, has been prepared and characterised; this integrated system affords both water-soluble stalk and ring components in an effort to improve the biocompatibility of these promising new drug delivery vehicles.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2009
Language
English
Article Type
Article
Keywords

DRUG-DELIVERY; SILICA NANOPARTICLES; MESOPOROUS SILICA; SUPRAMOLECULAR NANOVALVE; MOLECULAR MACHINE; BINDING; PSEUDOROTAXANES; STIMULI; GUEST; NANOMEDICINE

Citation

CHEMICAL COMMUNICATIONS, no.36, pp.5371 - 5373

ISSN
1359-7345
DOI
10.1039/b910431c
URI
http://hdl.handle.net/10203/94000
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