DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lim, KY | ko |
dc.contributor.author | Yang, JJ | ko |
dc.contributor.author | Lee, DS | ko |
dc.contributor.author | Noh, JS | ko |
dc.contributor.author | Jung, MW | ko |
dc.contributor.author | Chung, YK | ko |
dc.date.accessioned | 2013-03-08T13:40:38Z | - |
dc.date.available | 2013-03-08T13:40:38Z | - |
dc.date.created | 2013-02-20 | - |
dc.date.created | 2013-02-20 | - |
dc.date.issued | 2005-09 | - |
dc.identifier.citation | NEUROREPORT, v.16, pp.1605 - 1608 | - |
dc.identifier.issn | 0959-4965 | - |
dc.identifier.uri | http://hdl.handle.net/10203/93158 | - |
dc.description.abstract | Stress impairs the induction of long-term potentiation in the hippocampus as well as hippocampus-dependent memory. Lithium, a classical mood stabilizer, is known to have beneficial effects on stress-induced impairment of spatial memory. In the present study, we investigated lithium effects on the impairment of long-term potentiation induction after exposure to acute immobilization stress. As previously reported, immobilization stress impaired long-term potentiation induction in the CAI region of rat hippocampal slices. Treating the slices with 0.6 or 1 mM lithium attenuated impaired long-term potentiation induction in stressed animals. Lithium was without effect on long-term potentiation induction in unstressed animals or baseline synaptic responses in unstressed or stressed animals. These results demonstrate a protective effect of lithium against stress-induced impairment of long-term potentiation induction. | - |
dc.language | English | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | ACUTE RESTRAINT STRESS | - |
dc.subject | NEUROTROPHIC FACTOR | - |
dc.subject | HIPPOCAMPAL PLASTICITY | - |
dc.subject | MOOD STABILIZERS | - |
dc.subject | DENTATE GYRUS | - |
dc.subject | MEMORY | - |
dc.subject | RATS | - |
dc.subject | LTP | - |
dc.subject | ACTIVATION | - |
dc.subject | PKC | - |
dc.title | Lithium attenuates stress-induced impairment of long-term potentiation induction | - |
dc.type | Article | - |
dc.identifier.wosid | 000232505900015 | - |
dc.identifier.scopusid | 2-s2.0-28944433577 | - |
dc.type.rims | ART | - |
dc.citation.volume | 16 | - |
dc.citation.beginningpage | 1605 | - |
dc.citation.endingpage | 1608 | - |
dc.citation.publicationname | NEUROREPORT | - |
dc.identifier.doi | 10.1097/01.wnr.0000179078.54906.52 | - |
dc.contributor.localauthor | Jung, MW | - |
dc.contributor.nonIdAuthor | Lim, KY | - |
dc.contributor.nonIdAuthor | Yang, JJ | - |
dc.contributor.nonIdAuthor | Lee, DS | - |
dc.contributor.nonIdAuthor | Noh, JS | - |
dc.contributor.nonIdAuthor | Chung, YK | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | hippocampus | - |
dc.subject.keywordAuthor | lithium | - |
dc.subject.keywordAuthor | long-term potentiation | - |
dc.subject.keywordAuthor | stress | - |
dc.subject.keywordAuthor | synaptic plasticity | - |
dc.subject.keywordPlus | ACUTE RESTRAINT STRESS | - |
dc.subject.keywordPlus | NEUROTROPHIC FACTOR | - |
dc.subject.keywordPlus | HIPPOCAMPAL PLASTICITY | - |
dc.subject.keywordPlus | MOOD STABILIZERS | - |
dc.subject.keywordPlus | DENTATE GYRUS | - |
dc.subject.keywordPlus | MEMORY | - |
dc.subject.keywordPlus | RATS | - |
dc.subject.keywordPlus | LTP | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | PKC | - |
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