Rapid wavelength-swept spectrally encoded confocal microscopy

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Spectrally encoded confocal microscopy (SECM) is a technique that allows confocal microscopy to be performed through the confines of a narrow diameter optical fiber probe. We present a novel scheme for performing SECM in which a rapid wavelength swept source is used. The system allows large field of view images to be acquired at rates up to 30 frames/second. Images of resolution targets and tissue specimens acquired ex vivo demonstrate high lateral (1.4 mu m) and axial (6 mu m) resolution. Imaging of human skin was performed in vivo at depths of up to 350 mu m, allowing cellular and sub-cellular details to be visualized in real time. (c) 2005 Optical Society of America.
Publisher
OPTICAL SOC AMER
Issue Date
2005-10
Language
English
Article Type
Article
Keywords

IN-VIVO; REFLECTANCE MICROSCOPE; OPTICAL MICROSCOPE; HUMAN SKIN; LASER; MICROENDOSCOPE; DESIGN; FIBER; LENS

Citation

OPTICS EXPRESS, v.13, no.20, pp.8214 - 8221

ISSN
1094-4087
DOI
10.1364/OPEX.13.008214
URI
http://hdl.handle.net/10203/91079
Appears in Collection
ME-Journal Papers(저널논문)
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