The flow resistance of single DNA-grafted colloids as measured by optical tweezers

Cited 15 time in webofscience Cited 0 time in scopus
  • Hit : 240
  • Download : 0
In rheological experiments, the flow resistance of single blank or DNA-grafted colloids is determined and compared. The length of the double-stranded-DNA varies amongst 1,000, 4,000 and 6,000 base pairs (bp) corresponding to contour lengths varying between 340 and 2,040 nm at a grafting density of 0.03 +/- 0.01 mu m(2)/chain. The degree of swelling of the grafted DNA is adjusted by exchanging the ion concentration of the surrounding medium. For all examined flow velocities ranging, between 100 and 1,200 mu m/s, one observes an interesting deviation from Stokes law which can be traced back to a shear-dependent conformational change of the brush layer. The ratio of the effective hydrodynamic radii of DNA-grafted and blank colloids shows a pronounced dependence on the flow velocity, but as well on the length of the grafted DNA and the ionic strength of the solvent. The experimental findings are in qualitative agreement with hydrodynamic simulations based on an elastically jointed chain model.
Publisher
SPRINGER HEIDELBERG
Issue Date
2006-09
Language
English
Article Type
Article
Citation

MICROFLUIDICS AND NANOFLUIDICS, v.2, no.5, pp.381 - 386

ISSN
1613-4982
DOI
10.1007/s10404-006-0080-0
URI
http://hdl.handle.net/10203/90799
Appears in Collection
NT-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 15 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0