EXTRACTION OF INDOLE ALKALOIDS FROM CATHARANTHUS ROSEUS BY USING SUPERCRITICAL CARBON DIOXIDE

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Indole alkaloids, particularly vindoline and catharanthine, were extracted from the leaves ofCatharanthus roseus by supercritical extraction with CO2. The contents of vindoline and catharanthine in the extracts were determined by HPLC and identified by LC/MS. About 52 %(w/w) of the initial vindoline content, 1.5 mg vindoline/g dry wt leaves, was recovered after extracting this material for 10 h with the CO2 flow rate of 400 ml/min at 40°C and 150 bar. Vindoline concentration in the extract was 67 %(w/w).
Publisher
Springer Verlag (Germany)
Issue Date
1992-03
Citation

BIOTECHNOLOGY TECHNIQUES, Vol.6 No.2, pp.127-130

ISSN
0951-208X
DOI
10.1007/BF02438817
URI
http://hdl.handle.net/10203/9079
Appears in Collection
CBE-Journal Papers(저널논문)

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