Microrheology of red blood cell membranes using dynamic scattering microscopy

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We employ a novel optical technique, dynamic scattering microscopy (DSM), to extract the frequency dependence of the viscoelastic modulus associated with the red blood cell membrane. This approach applies the principle of dynamic light scattering to micro beads attached to the red blood cell membrane in thermal fluctuation. This allows for high-throughput characterization of a large number of cells simultaneously, which represents a significant advantage over current methods. The results in terms of the effective loss and storage moduli indicate the generic behavior of a viscoelastic material, characterized by power laws with exponents between 0 and 1. (c) 2007 Optical Society of America.
Publisher
OPTICAL SOC AMER
Issue Date
2007-12
Language
English
Article Type
Article
Citation

OPTICS EXPRESS, v.15, no.25, pp.17001 - 17009

ISSN
1094-4087
DOI
10.1364/OE.15.017001
URI
http://hdl.handle.net/10203/88689
Appears in Collection
PH-Journal Papers(저널논문)
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