An asymmetric aminohydroxylation approach to the stereoselective synthesis of cis-substituted azetidinone of loracarbef
A formal synthesis of loracarbef is described. The required key cia-substituted azetidinone skeleton was stereoselectively constructed via p-amino acid, which was provided from the asymmetric aminohydroxylation of alpha,beta -unsaturated ester. (C) 2001 Elsevier Science Ltd. All rights reserved.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 2001-07
- Language
- English
- Article Type
- Article
- Keywords
CARBACEPHEM FRAMEWORK; AMINO ACIDS
- Citation
TETRAHEDRON LETTERS, v.42, no.27, pp.4519 - 4521
- ISSN
- 0040-4039
- Appears in Collection
- CH-Journal Papers(저널논문)
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