DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, JH | ko |
dc.contributor.author | Park, IY | ko |
dc.contributor.author | Kim, MS | ko |
dc.contributor.author | Kim, Sun-Chang | ko |
dc.date.accessioned | 2013-03-04T15:10:54Z | - |
dc.date.available | 2013-03-04T15:10:54Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2002-11 | - |
dc.identifier.citation | FEBS LETTERS, v.531, no.3, pp.459 - 463 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.uri | http://hdl.handle.net/10203/83033 | - |
dc.description.abstract | A 19-residue antimicrobial peptide parasin I is generated from histone H2A in the skin mucus of catfish by the action of cathepsin D activated by a procathepsin D-processing enzyme induced upon epidermal injury. Here we report the isolation and characterization of the procathepsin D-processing enzyme in the mucus of wounded catfish. Sequence analysis of the cDNA identified the purified procathepsin D-processing enzyme as matrix metalloproteinase 2 (MMP 2). By acting as a procathepsin D convertase upon epidermal injury, MMP 2 is involved in the regulation of parasin I production in catfish skin mucosa. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | INNATE HOST-DEFENSE | - |
dc.subject | HISTONE H2A | - |
dc.subject | PLEUROCIDIN | - |
dc.subject | ACTIVATION | - |
dc.subject | FLOUNDER | - |
dc.title | Matrix metalloproteinase 2 is involved in the regulation of the antimicrobial peptide parasin I production in catfish skin mucosa | - |
dc.type | Article | - |
dc.identifier.wosid | 000179486300015 | - |
dc.identifier.scopusid | 2-s2.0-0037145813 | - |
dc.type.rims | ART | - |
dc.citation.volume | 531 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 459 | - |
dc.citation.endingpage | 463 | - |
dc.citation.publicationname | FEBS LETTERS | - |
dc.contributor.localauthor | Kim, Sun-Chang | - |
dc.contributor.nonIdAuthor | Cho, JH | - |
dc.contributor.nonIdAuthor | Park, IY | - |
dc.contributor.nonIdAuthor | Kim, MS | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | antimicrobial peptide | - |
dc.subject.keywordAuthor | cathepsin D | - |
dc.subject.keywordAuthor | historic H2A | - |
dc.subject.keywordAuthor | matrix metalloproteinase 2 | - |
dc.subject.keywordAuthor | parasin I | - |
dc.subject.keywordPlus | INNATE HOST-DEFENSE | - |
dc.subject.keywordPlus | HISTONE H2A | - |
dc.subject.keywordPlus | PLEUROCIDIN | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | FLOUNDER | - |
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