DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, SungHo | ko |
dc.contributor.author | Kang, SY | ko |
dc.contributor.author | Choi, HW | ko |
dc.contributor.author | Kim, CM | ko |
dc.contributor.author | Jun, HS | ko |
dc.contributor.author | Youn, JH | ko |
dc.date.accessioned | 2013-03-04T14:31:01Z | - |
dc.date.available | 2013-03-04T14:31:01Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2004-05 | - |
dc.identifier.citation | SYNTHESIS-STUTTGART, v.25, no.7, pp.1102 - 1114 | - |
dc.identifier.issn | 0039-7881 | - |
dc.identifier.uri | http://hdl.handle.net/10203/82954 | - |
dc.description.abstract | The natural (+)-lasonolide A (1), an anti-tumor agent, has been synthesized via thermodynamic benzylidene formation at the C-22 quaternary chiral center, use of a disulfone equivalent for elongation of the C-15-C-17 three-carbon chain as well as introduction of the two trans olefins at C-15 and C-17, iodocyclization for the upper THP, Michael addition for the bottom THP, and intramolecular Horner-Emmons olefination for the 20-membered macrolactone. | - |
dc.language | English | - |
dc.publisher | GEORG THIEME VERLAG KG | - |
dc.subject | LASONOLIDE-A | - |
dc.subject | STEREOCONTROLLED SYNTHESIS | - |
dc.subject | HOMOALLYLIC ALCOHOLS | - |
dc.subject | ASYMMETRIC-SYNTHESIS | - |
dc.subject | HYDROXY FUNCTIONS | - |
dc.subject | PROTECTING GROUPS | - |
dc.subject | CHIRAL SYNTHESIS | - |
dc.subject | MACROLIDE | - |
dc.subject | MACROCYCLIZATION | - |
dc.subject | OLEFINATION | - |
dc.title | Stereoselective total synthesis of the natural (+)-lasonolide A | - |
dc.type | Article | - |
dc.identifier.wosid | 000221429700025 | - |
dc.type.rims | ART | - |
dc.citation.volume | 25 | - |
dc.citation.issue | 7 | - |
dc.citation.beginningpage | 1102 | - |
dc.citation.endingpage | 1114 | - |
dc.citation.publicationname | SYNTHESIS-STUTTGART | - |
dc.identifier.doi | 10.1055/s-2004-822340 | - |
dc.contributor.localauthor | Kang, SungHo | - |
dc.contributor.nonIdAuthor | Kang, SY | - |
dc.contributor.nonIdAuthor | Choi, HW | - |
dc.contributor.nonIdAuthor | Kim, CM | - |
dc.contributor.nonIdAuthor | Jun, HS | - |
dc.contributor.nonIdAuthor | Youn, JH | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | asymmetric synthesis | - |
dc.subject.keywordAuthor | diastereomeric differentiation | - |
dc.subject.keywordAuthor | macrocyclization | - |
dc.subject.keywordAuthor | natural products | - |
dc.subject.keywordAuthor | total synthesis | - |
dc.subject.keywordPlus | LASONOLIDE-A | - |
dc.subject.keywordPlus | STEREOCONTROLLED SYNTHESIS | - |
dc.subject.keywordPlus | HOMOALLYLIC ALCOHOLS | - |
dc.subject.keywordPlus | ASYMMETRIC-SYNTHESIS | - |
dc.subject.keywordPlus | HYDROXY FUNCTIONS | - |
dc.subject.keywordPlus | PROTECTING GROUPS | - |
dc.subject.keywordPlus | CHIRAL SYNTHESIS | - |
dc.subject.keywordPlus | MACROLIDE | - |
dc.subject.keywordPlus | MACROCYCLIZATION | - |
dc.subject.keywordPlus | OLEFINATION | - |
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