DSpace at KOASAS
College of Life Science and Bioengineering(생명과학기술대학)Dept. of Biological Sciences(생명과학과)BS-Journal Papers(저널논문)

Differential inheritance modes of DNA methylation between euchromatic and heterochromatic DNA sequences in ageing fetal bovine fibroblasts

Cited 11 time in webofscience Cited 13 time in scopus
  • Hit : 389
  • Download : 0
Export
DC FieldValueLanguage
dc.contributor.authorKang, Yong-Kookko
dc.contributor.authorKoo, Deog-Bonko
dc.contributor.authorPark, Jung Sunko
dc.contributor.authorChoi, Young-Heeko
dc.contributor.authorLee, Kyung-Kwangko
dc.contributor.authorHan, Yong Mahnko
dc.date.accessioned2013-03-04T04:30:17Z-
dc.date.available2013-03-04T04:30:17Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2001-06-
dc.identifier.citationFEBS LETTERS, v.498, no.1, pp.1 - 5-
dc.identifier.issn0014-5793-
dc.identifier.urihttp://hdl.handle.net/10203/81901-
dc.description.abstractTo elucidate overall changes in DNA methylation occurring by inappropriate epigenetic control during ageing, we compared fetal bovine fibroblasts and their aged neomycin-resistant versions using bisulfite-PCR technology. Reduction in DNA methylation,vas observed in euchromatic repeats (18SrRNAlart2) and promoter regions of single-copy genes (the cytokeratin/beta -lactoglobulin/interleukin-13 genes). Contrastingly, a stable maintenance of DNA methylation was revealed in various heterochromatic sequences (satellite I/II/alphoid and Bov-B). The differential inheritance mode of DNA methylation was confirmed through the analysis of individual neomycin-resistant clones. These global, multi-locus analyses provide evidence on the tendency of differential epigenetic modification between genomic DNA regions during ageing. (C) 2001 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE BV-
dc.subjectC-MYC GENE-
dc.subjectREPEAT-
dc.subjectALU-
dc.subjectORGANIZATION-
dc.subjectEVOLUTION-
dc.subjectPATTERNS-
dc.subjectCANCER-
dc.subjectL1-
dc.titleDifferential inheritance modes of DNA methylation between euchromatic and heterochromatic DNA sequences in ageing fetal bovine fibroblasts-
dc.typeArticle-
dc.identifier.wosid000169258400001-
dc.identifier.scopusid2-s2.0-0035370119-
dc.type.rimsART-
dc.citation.volume498-
dc.citation.issue1-
dc.citation.beginningpage1-
dc.citation.endingpage5-
dc.citation.publicationnameFEBS LETTERS-
dc.identifier.doi10.1016/S0014-5793(01)02472-3-
dc.contributor.localauthorHan, Yong Mahn-
dc.contributor.nonIdAuthorKang, Yong-Kook-
dc.contributor.nonIdAuthorKoo, Deog-Bon-
dc.contributor.nonIdAuthorPark, Jung Sun-
dc.contributor.nonIdAuthorChoi, Young-Hee-
dc.contributor.nonIdAuthorLee, Kyung-Kwang-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorageing-
dc.subject.keywordAuthormethylation-
dc.subject.keywordAuthorepigenetic modification-
dc.subject.keywordAuthoreuchromatin-
dc.subject.keywordAuthorheterochromatin-
dc.subject.keywordPlusC-MYC GENE-
dc.subject.keywordPlusREPEAT-
dc.subject.keywordPlusALU-
dc.subject.keywordPlusORGANIZATION-
dc.subject.keywordPlusEVOLUTION-
dc.subject.keywordPlusPATTERNS-
dc.subject.keywordPlusCANCER-
dc.subject.keywordPlusL1-
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 11 items in WoS Click to see citing articles in records_button

Display Simple Item Record

qr_code

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


rss_1.0 rss_2.0 atom_1.0