Enzymatic synthesis of 3-O-methyl-4-O-beta-D-galactopyranosyl-D-glucose (3-O-methyl-lactose); a potential agent for the assessment of intestinal lactase activity

Cited 2 time in webofscience Cited 0 time in scopus
  • Hit : 218
  • Download : 0
DC FieldValueLanguage
dc.contributor.authorYoon, JHko
dc.contributor.authorRyu, GHko
dc.contributor.authorFinch, Pko
dc.contributor.authorRhee, Joon Shickko
dc.date.accessioned2013-03-03T20:27:04Z-
dc.date.available2013-03-03T20:27:04Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2001-11-
dc.identifier.citationJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, v.15, no.4-6, pp.191 - 196-
dc.identifier.issn1381-1177-
dc.identifier.urihttp://hdl.handle.net/10203/80296-
dc.description.abstractEnzymatic synthesis of 3-O-methyl-4-O-beta -D-galactopyranosyl-D-glucose (3-O-methyl-lactose) has been attempted using both galactosyltransferase and galactosidase activities. The transferase-catalysed reaction produces exclusively the desired product in beta -1,4-glycosidic linkage whereas the galactosidase-catalysed reactions predominantly form a 1,6-linked disaccharide. With galactosidase, in order to change the regioselectivity, blocking of the 6-position of 3-O-methyl-D-glucose and anomeric modification of the acceptor structure were investigated. Although acetylation of the 6-position of 3-O-methyl glucose catalysed by lipase was successful, the synthesis of the desired disaccharide did not occur. (C) 2001 Elsevier Science B.V. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE BV-
dc.subjectSUBSTRATE-SPECIFICITY-
dc.subjectACCEPTOR SPECIFICITY-
dc.subjectBETA-GALACTOSIDASES-
dc.subjectN-ACETYLLACTOSAMINE-
dc.subjectLACTOSE HYDROLYSIS-
dc.subjectENZYMIC-SYNTHESIS-
dc.subjectGLYCOSIDES-
dc.subjectDISACCHARIDES-
dc.subjectHYDROGEN-
dc.titleEnzymatic synthesis of 3-O-methyl-4-O-beta-D-galactopyranosyl-D-glucose (3-O-methyl-lactose); a potential agent for the assessment of intestinal lactase activity-
dc.typeArticle-
dc.identifier.wosid000171658200010-
dc.type.rimsART-
dc.citation.volume15-
dc.citation.issue4-6-
dc.citation.beginningpage191-
dc.citation.endingpage196-
dc.citation.publicationnameJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC-
dc.identifier.doi10.1016/S1381-1177(01)00028-5-
dc.contributor.nonIdAuthorYoon, JH-
dc.contributor.nonIdAuthorRyu, GH-
dc.contributor.nonIdAuthorFinch, P-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorlactasia-
dc.subject.keywordAuthorenzymatic synthesis-
dc.subject.keywordAuthorgalactosyltransferase-
dc.subject.keywordAuthorbeta-galactosidase-
dc.subject.keywordAuthor3-O-methyl-lactose-
dc.subject.keywordPlusSUBSTRATE-SPECIFICITY-
dc.subject.keywordPlusACCEPTOR SPECIFICITY-
dc.subject.keywordPlusBETA-GALACTOSIDASES-
dc.subject.keywordPlusN-ACETYLLACTOSAMINE-
dc.subject.keywordPlusLACTOSE HYDROLYSIS-
dc.subject.keywordPlusENZYMIC-SYNTHESIS-
dc.subject.keywordPlusGLYCOSIDES-
dc.subject.keywordPlusDISACCHARIDES-
dc.subject.keywordPlusHYDROGEN-
Appears in Collection
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 2 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0