A practical total synthesis of gelastatins
The first and practical total synthesis of gelastatins 1, a novel matrix metalloproteinase inhibitor possessing antitumor activity. was accomplished in nine steps starting from Meldrum's acid. (C) 2003 Elsevier Ltd. All rights reserved.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 2003-07
- Language
- English
- Article Type
- Article
- Keywords
MATRIX-METALLOPROTEINASE INHIBITORS; WESTERDYKELLA-MULTISPORA F50733; SILYL ENOL ETHERS; THERAPEUTIC APPLICATION; DYKELLIC ACID; OLEFINS; SKELETON; LACTONES; DESIGN; ALPHA
- Citation
TETRAHEDRON LETTERS, v.44, no.32, pp.5803 - 5806
- ISSN
- 0040-4039
- Appears in Collection
- CH-Journal Papers(저널논문)
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