DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Injune | ko |
dc.contributor.author | Kwak, HJ | ko |
dc.contributor.author | Ahn, JE | ko |
dc.contributor.author | So, JN | ko |
dc.contributor.author | Liu, MZ | ko |
dc.contributor.author | Koh, KN | ko |
dc.contributor.author | Koh, GY | ko |
dc.date.accessioned | 2013-03-03T07:22:28Z | - |
dc.date.available | 2013-03-03T07:22:28Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1999-01 | - |
dc.identifier.citation | FEBS LETTERS, v.443, no.3, pp.353 - 356 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.uri | http://hdl.handle.net/10203/77759 | - |
dc.description.abstract | Using homology-based PCR, we have isolated cDNA encoding a novel member (491 amino acids) of the angiopoietin (Ang) family from human adult heart cDNA and have designated it angiopoietin-3 (Ang3). The NH2-terminal and COOH-terminal portions of Ang-3 contain the characteristic coiled-coil domain and fibrinogen-like domain that are conserved in other known Angs. Ang3 has a highly hydrophobic region at the N-terminus (similar to 21 amino acids) that is typical of a signal sequence for protein secretion. Ang3 mRNA is most abundant in adrenal gland, placenta, thyroid gland, heart and small intestine in human adult tissues. Additionally, Ang3 is a secretory protein, but is not a mitogen in endothelial cells. (C) 1999 Federation of European Biochemical Societies. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | ENDOTHELIAL-CELLS | - |
dc.subject | TIE2 RECEPTOR | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | LIGAND | - |
dc.title | Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3 | - |
dc.type | Article | - |
dc.identifier.wosid | 000078501700023 | - |
dc.identifier.scopusid | 2-s2.0-0032998010 | - |
dc.type.rims | ART | - |
dc.citation.volume | 443 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 353 | - |
dc.citation.endingpage | 356 | - |
dc.citation.publicationname | FEBS LETTERS | - |
dc.identifier.doi | 10.1016/S0014-5793(99)00008-3 | - |
dc.contributor.localauthor | Kim, Injune | - |
dc.contributor.nonIdAuthor | Kwak, HJ | - |
dc.contributor.nonIdAuthor | Ahn, JE | - |
dc.contributor.nonIdAuthor | So, JN | - |
dc.contributor.nonIdAuthor | Liu, MZ | - |
dc.contributor.nonIdAuthor | Koh, KN | - |
dc.contributor.nonIdAuthor | Koh, GY | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | angiopoietin | - |
dc.subject.keywordAuthor | endothelial cell | - |
dc.subject.keywordAuthor | vasculogenesis | - |
dc.subject.keywordPlus | ENDOTHELIAL-CELLS | - |
dc.subject.keywordPlus | TIE2 RECEPTOR | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | LIGAND | - |
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