DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwak, HJ | ko |
dc.contributor.author | So, JN | ko |
dc.contributor.author | Lee, SJ | ko |
dc.contributor.author | Kim, Injune | ko |
dc.contributor.author | Koh, Gou Young | ko |
dc.date.accessioned | 2013-03-03T06:11:36Z | - |
dc.date.available | 2013-03-03T06:11:36Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1999-04 | - |
dc.identifier.citation | FEBS LETTERS, v.448, no.2-3, pp.249 - 253 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.uri | http://hdl.handle.net/10203/77577 | - |
dc.description.abstract | We examined the effect of angiopoietin-1 (Ang1) on apoptosis in human umbilical vein endothelial cells (HUVECs). Ang1 (5-1000 ng/ml) dose-dependently inhibited apoptosis under a serum-deprived state. A significant apoptotic inhibition occurred with as low as 50 ng/ml. Two hundred ng/ml of Ang1 inhibited to approximately 50% of the control apoptotic rates for 96 h. Furthermore, an augmented antiapoptotic effect of Ang1 by the addition of 20 ng/ml vascular endothelial growth factor was observed. This Ang1-iuduced strong antiapoptotic effect in endothelial cells is a novel and intriguing finding and could be an additional description of Ang1-induced direct biological function. (C) 1999 Federation of European Biochemical Societies. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | GROWTH-FACTOR | - |
dc.subject | TIE2 RECEPTOR | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | EXPRESSION | - |
dc.subject | INHIBITION | - |
dc.subject | CYTOKINES | - |
dc.subject | BIOLOGY | - |
dc.subject | LIGAND | - |
dc.subject | SYSTEM | - |
dc.title | Angiopoietin-1 is an apoptosis survival factor for endothelial cells | - |
dc.type | Article | - |
dc.identifier.wosid | 000079782900010 | - |
dc.identifier.scopusid | 2-s2.0-0032926320 | - |
dc.type.rims | ART | - |
dc.citation.volume | 448 | - |
dc.citation.issue | 2-3 | - |
dc.citation.beginningpage | 249 | - |
dc.citation.endingpage | 253 | - |
dc.citation.publicationname | FEBS LETTERS | - |
dc.identifier.doi | 10.1016/S0014-5793(99)00378-6 | - |
dc.contributor.localauthor | Kim, Injune | - |
dc.contributor.localauthor | Koh, Gou Young | - |
dc.contributor.nonIdAuthor | Kwak, HJ | - |
dc.contributor.nonIdAuthor | So, JN | - |
dc.contributor.nonIdAuthor | Lee, SJ | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | angiopoietin | - |
dc.subject.keywordAuthor | apoptosis | - |
dc.subject.keywordAuthor | endothelial cell | - |
dc.subject.keywordPlus | GROWTH-FACTOR | - |
dc.subject.keywordPlus | TIE2 RECEPTOR | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | CYTOKINES | - |
dc.subject.keywordPlus | BIOLOGY | - |
dc.subject.keywordPlus | LIGAND | - |
dc.subject.keywordPlus | SYSTEM | - |
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