The analysis of prestressed box-girder bridges using the spline finite strip method is presented. In the present study, the spline finite strip method is modified by using the non-periodic B-spline interpolation. In the analysis of the prestressed box-girder bridges, the short-term losses of prestressing are considered and each tendon force at the tendon point is evaluated by summation of the adjacent segment forces. Once the equivalent forces acting on the structure at the tendon points are found, they are transformed into statically equivalent forces at the adjacent node of nodal line. Several examples were analyzed to verify the performance of present method. Good agreements were obtained when compared with the previous studies. (C) 2002 Published by Elsevier Science Ltd.