Lipase-catalyzed Synthesis of Lysophosphatidic Acid in a Solvent-free System
The direct, lipase-catalyzed esterifications of glycerol-3-phosphate in an organic solvent system and in an solvent free system were carried out. In a solvent free system only, LPA synthesis could be achieved within the acceptable reaction time. Open reaction system was preferable to closed reaction system for LPA synthesis. Yield of LPA isolated by silica gel column chromatography was 32.3%.
- Publisher
- Springer
- Issue Date
- 1995
- Language
- English
- Article Type
- Article
- Keywords
PHOSPHATIDYLCHOLINE; ACYL
- Citation
BIOTECHNOLOGY LETTERS, v.17, no.5, pp.531 - 536
- ISSN
- 0141-5492
- Appears in Collection
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