Nucleotide sequence of exon 2 to 4 of the R-ras gene in the hermaphroditic fish Rivulus marmoratus

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We have cloned the ras homologue from the mangrove rivulus (Rivulus marmoratus) after low-stringency plaque hybridization of the mangrove rivulus genomic DNA library. This mangrove rivulus ras homologue showed a 76% amino acid homology to the human R(related)-ras gene with identical exon/intron boundary and was named the mangrove rivulus R-ras gene. The mangrove rivulus R-ras gene spanned 1.8 kb and consisted of at least 5 exons. The exon/intron boundaries coincided with the rule of GT/AG of consensus splice acceptor and donor sequences. To our knowledge this is the first report that fish also have the R-ras gene with identical exon/intron boundaries and extensive homology with human.
Publisher
HARWOOD ACAD PUBL GMBH
Issue Date
1998-06
Language
English
Article Type
Article
Keywords

RAINBOW-TROUT LIVER; ONCOGENES; MUTATIONS; PROTOONCOGENE; ACTIVATION; EXPRESSION; TELEOSTEI; RIVULIDAE; FLOUNDER; CANCER

Citation

DNA SEQUENCE, v.8, no.4, pp.229 - 234

ISSN
1042-5179
URI
http://hdl.handle.net/10203/68293
Appears in Collection
BS-Journal Papers(저널논문)
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