A new antitumor agent: Methyl sulfonium perchlorate of echinomeycin
Newly modified-echinomycin such as S-methylated sulfonium perchlorate of echinomycin (1), monosulfoxide (2), disulfoxide (3) and sulfone (4) have been prepared and evaluated for in vitro biological activities of cytotoxicity against P388, B16 and SNU-16 as well as in vivo antitumor activity against murine leukemia P388 and melanoma B16. (C) 1998 Elsevier Science Ltd. All rights reserved.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 1998-04
- Language
- English
- Article Type
- Article
- Keywords
ECHINOMYCIN
- Citation
BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.8, no.7, pp.731 - 734
- ISSN
- 0960-894X
- Appears in Collection
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