New cyclization of N-hydroxyiminoyl chlorides with N-alkryl ethynesulfonamides: Synthesis of 4-alkyl-3-aryl-4,5-dihydro-1,5,2,4-oxathiadiazepine-5,5-diones

Abstract

N-Hydroxyiminoyl chlorides reacted With N-alkyl ethynesulfonamides in the presence of triethylamine in CH,CZ, to afford the 4-alkyl-3-aryl-4,5dihydro-1,5,2,4-oxathiadiazepine-5, 5-diones (3) as the major products together with N-alkyl-3-aryl-5-isoxazolesulfonamides (4). (C) 1999 John Wiley & Sons, Inc.