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Showing results 1 to 7 of 7

1
A rationally designed small molecule for identifying an in vivo link between metal-amyloid-beta complexes and the pathogenesis of Alzheimer's disease

Beck, Michael W.; Oh, Shin Bi; Kerr, Richard A.; Lee, Hyuck Jin; Kim, So Hee; Kim, Sujeong; Jang, Milim; et al, CHEMICAL SCIENCE, v.6, no.3, pp.1879 - 1886, 2015-03

2
A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms

Derrick, Jeffrey S.; Kerr, Richard A.; Nam, Younwoo; Oh, Shin Bi; Lee, Hyuck Jin; Earnest, Kaylin G.; Suh, Nayoung; et al, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.46, pp.14785 - 14797, 2015-11

3
Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-beta aggregation

Lee, Hyuck Jin; Kerr, Richard A.; Korshavn, Kyle J.; Lee, Jeeyeon; Kang, Juhye; Ramamoorthy, Ayyalusamy; Ruotolo, Brandon T.; et al, INORGANIC CHEMISTRY FRONTIERS, v.3, no.3, pp.381 - 392, 2016-03

4
Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-beta, and Oxidative Stress in Alzheimer's Disease

Derrick, Jeffrey S.; Kerr, Richard A.; Korshavn, Kyle J.; McLane, Michael J.; Kang, Juhye; Nam, Eunju; Ramamoorthy, Ayyalusamy; et al, INORGANIC CHEMISTRY, v.55, no.10, pp.5000 - 5013, 2016-05

5
Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease

Beck, Michael W.; Derrick, Jeffrey S.; Suh, Jong-Min; Kim, Mingeun; Korshavn, Kyle J.; Kerr, Richard A.; Cho, Woo Jong; et al, CHEMMEDCHEM, v.12, no.22, pp.1828 - 1838, 2017-11

6
Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease

Lee, Hyuck Jin; Korshavn, Kyle J.; Nam, Younwoo; Kang, Juhye; Paul, Thomas J.; Kerr, Richard A.; Youn, Il Seung; et al, CHEMISTRY-A EUROPEAN JOURNAL, v.23, no.11, pp.2706 - 2715, 2017-02

7
Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease

Beck, Michael W.; Derrick, Jeffrey S.; Kerr, Richard A.; Oh, Shin Bi; Cho, Woo Jong; Lee, Shin Jung C.; Ji, Yonghwan; et al, NATURE COMMUNICATIONS, v.7, 2016-10

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