Browse "Dept. of Biological Sciences(생명과학과)" by Author Lee, Jae Seong

Showing results 1 to 15 of 15

1
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes

Karottki, Karen Julie la Cour; Hefzi, Hooman; Li, Songyuan; Pedersen, Lasse Ebdrup; Spahn, Philipp N.; Joshi, Chintan; Ruckerbauer, David; et al, METABOLIC ENGINEERING, v.66, pp.114 - 122, 2021-07

2
Accelerated Homology-Directed Targeted Integration of Transgenes in Chinese Hamster Ovary Cells Via CRISPR/Cas9 and Fluorescent Enrichment

Lee, Jae Seong; Grav, Lise Marie; Pedersen, Lasse Ebdrup; Lee, Gyun Min; Kildegaard, Helene Faustrup, BIOTECHNOLOGY AND BIOENGINEERING, v.113, no.11, pp.2518 - 2523, 2016-11

3
An optimized genome-wide, virus-free CRISPR screen for mammalian cells

Xiong, Kai; la Cour Karottki, Karen Julie; Hefzi, Hooman; Li, Songyuan; Grav, Lise Marie; Li, Shangzhong; Spahn, Philipp; et al, Cell Reports Methods, v.1, no.4, 2021-08

4
Awakening dormant glycosyltransferases in CHO cells with CRISPRa

Karottki, Karen Julie la Cour; Hefzi, Hooman; Xiong, Kai; Shamie, Isaac; Hansen, Anders Holmgaard; Li, Songyuan; Pedersen, Lasse Ebdrup; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.117, no.2, pp.593 - 598, 2020-02

5
Chemical Inhibition of Autophagy: Examining Its Potential to Increase the Specific Productivity of Recombinant CHO Cell Lines

Baek, Eric H; Kim, Che Lin; Kim, Mi Gyeom; Lee, Jae Seong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.113, no.9, pp.1953 - 1961, 2016-09

6
Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells

Shin, Seunghyeon; Kim, Su Hyun; Shin, Sung Wook; Grav, Lise Marie; Pedersen, Lasse Ebdrup; Lee, Jae Seong; Lee, Gyun Min, ACS SYNTHETIC BIOLOGY, v.9, no.6, pp.1263 - 1269, 2020-06

7
Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening

Kim, Su Hyun; Shin, Seunghyeon; Baek, Minhye; Xiong, Kai; Karottki, Karen Julie la Cour; Hefzi, Hooman; Grav, Lise Marie; et al, METABOLIC ENGINEERING, v.80, pp.66 - 77, 2023-11

8
Improving the secretory capacity of CHO producer cells: The effect of controlled Blimp1 expression, a master transcription factor for plasma cells

Kim, Su Hyun; Baek, Minhye; Park, Sungje; Shin, Seunghyeon; Lee, Jae Seong; Lee, Gyun Min, METABOLIC ENGINEERING, v.69, pp.73 - 86, 2022-01

9
Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation

Grav, Lise Marie; Sergeeva, Dania; Lee, Jae Seong; de Mas, Igor Marin; Lewis, Nathan E.; Andersen, Mikael Rordam; Nielsen, Lars Keld; et al, ACS SYNTHETIC BIOLOGY, v.7, no.9, pp.2148 - 2159, 2018-09

10
Mitigating Clonal Variation in Recombinant Mammalian Cell Lines

Lee, Jae Seong; Kildegaard, Helene Faustrup; Lewis, Nathan E.; Lee, Gyun Min, TRENDS IN BIOTECHNOLOGY, v.37, no.9, pp.931 - 942, 2019-09

11
One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment

Grav, Lise Marie; Lee, Jae Seong; Gerling, Signe; Kallehauge, Thomas Beuchert; Hansen, Anders Holmgaard; Kol, Stefan; Lee, Gyun Min; et al, BIOTECHNOLOGY JOURNAL, v.10, no.9, pp.1446 - 1456, 2015-09

12
Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress

Shin, Seunghyeon; Kim, Su Hyun; Park, Jong-Ho; Lee, Jae Seong; Lee, Gyun Min, METABOLIC ENGINEERING, v.72, pp.247 - 258, 2022-07

13
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference

Xiong, Kai; Marquart, Kim Fabiano; Karottki, Karen Julie la Cour; Li, Shangzhong; Shamie, Isaac; Lee, Jae Seong; Gerling, Signe; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.116, no.7, pp.1813 - 1819, 2019-06

14
Streamlined Human Cell-Based Recombinase-Mediated Cassette Exchange Platform Enables Multigene Expression for the Production of Therapeutic Proteins

Shin, Seunghyeon; Kim, Su Hyun; Lee, Jae Seong; Lee, Gyun Min, ACS SYNTHETIC BIOLOGY, v.10, no.7, pp.1715 - 1727, 2021-07

15
Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine

Baek, Eric H; Lee, Jae Seong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.9, pp.2243 - 2254, 2018-09

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