DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Cho, I-Whan | - |
dc.contributor.advisor | 조의환 | - |
dc.contributor.author | Kim, Young-Dae | - |
dc.contributor.author | 김영대 | - |
dc.date.accessioned | 2011-12-15 | - |
dc.date.available | 2011-12-15 | - |
dc.date.issued | 1998 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=158758&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/49773 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 신소재공학과고분자전공, 1998.2, [ xix, 223 p. ] | - |
dc.description.abstract | Four different novel tocopherol-containing single-chain nonionic amphiphilic monomers, N-[methyl-N-(tocopheryloxycarbonyl)methyl amino]ethyl methacrylate (TOM), N-[methyl-N-[tocopheryloxypoly (ethyleneoxy)carbonyl]methylamino]ethyl methacrylates (n=2, TOPM-2; n=5, TOPM-5; n=10, TOPM-10: n=mean moles of EO) were synthesized by the reaction of α-tocopherol derivatives and DMEMA, characterized by FT $1^H$ and ${13}^C$ NMR spectroscopy, FT IR spectroscopy, elemental analysis, and mass spectroscopy, and used for the formation of bilayer vesicles. The unpolymerized vesicles of these single-chain amphiphiles even though they have a single-chain tocopherol as a hydrophobic group showed evidences of closed bilayer vesicles, which were converted to well-defined closed polymeric vesicles having distinct morphology, enhanced stability and reduced permeability upon polymerization either by thermal polymerization with free radical initiator AIBN or KPS or by direct UV-irradiated (220-400nm) photopolymerization. The apparent weight-average molecular weights of polymers formed in the polymerized vesicles of TOM, TOPM-2, 5, 10, and TOM/TOPM-10(1:2) determined by GPC using toluene as an eluent were in the range of 47,100 and 401,800 g/mol and molecular weight polydispersity of these polymers were in the range of 1.5 and 4.1. Conversions of these polymers were in the range of 44 and 85 %. Phase transition temperatures ($T_c$) of polymerized vesicles of these amphiphiles were in the range of 55 and 77 ℃, which are rather higher values than those of their unpolymerized counterparts, 41 and 68 ℃. Uranyl acetate stained TEM photographs showed that polymerization of unpolymerized vesicles of TOM of led to the formation of mostly spherical polymeric vesicles having diameters below 600 Å and and those of TOPM-2, -5, -10, and TOM/TOPM-10(1:2) led to the formation of relatively small spherical polymeric vesicles having diameters below 500 Å and relatively large elliptic polymeric vesicles... | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Vesicles | - |
dc.subject | Syntheses | - |
dc.subject | Amphiphilic polymers | - |
dc.subject | Tocopherol-containing | - |
dc.subject | Antioxidative activity | - |
dc.subject | 항산화력 | - |
dc.subject | 베시클 | - |
dc.subject | 합성 | - |
dc.subject | 양친매성 고분자 | - |
dc.subject | 토코페롤 함유 | - |
dc.title | Tocopherol-containing amphiphilic polymers: syntheses and vesicle-forming properties | - |
dc.title.alternative | 토코페롤을 함유한 양친매성 고분자의 합성과 베시클형성 특성 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 158758/325007 | - |
dc.description.department | 한국과학기술원 : 신소재공학과고분자전공, | - |
dc.identifier.uid | 000949001 | - |
dc.contributor.localauthor | Kim, Young-Dae | - |
dc.contributor.localauthor | 김영대 | - |
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