Study of 600 MHz NMR microscopy and its application to many subjects600 MHz NMR 현미경에 관한 연구와 여러 시료에의 적용

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We obtained a 1㎛ resolution NMR microscopy image for a silicon artificial microstructure filled with silicon oil within 8 hours at 14.1 T. The silicon structure was designed and fabricated to demonstrate the obtainable high resolution. The home built probe was made to give 1000 G/cm gradient field strength and a high sensitivity rf coil circuit was designed inside the probe. In this paper, we will investigate the factors and barriers in achieving 1㎛ resolution image and verify its resolution based on its factors. In order to achieve high resolution image, relevant liquid having low diffusion coefficient and T1, in our case, the silicon oil, was used. Pulse sequence was designed in consideration of bandwidth, diffusion coefficients, $T_1$, $T_2$ relaxation of the medium. We have also applied our home built probe to image biological animals such as earthworms in micrometer orders and verified its resolution. This can be an important achievement since vivo cellular imaging would be possible on this scale.
Advisors
Lee, Yong-HeeresearcherLee, Soon-Chilresearcher이용희researcher이순칠researcher
Description
한국과학기술원 : 물리학과,
Publisher
한국과학기술원
Issue Date
2001
Identifier
169392/325007 / 000993145
Language
eng
Description

학위논문(석사) - 한국과학기술원 : 물리학과, 2001.8, [ ii, 54 p. ]

Keywords

micron resolution; MRI; diffusion analysis; 현미경; NMR; Microscopy; 자기공명

URI
http://hdl.handle.net/10203/48577
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=169392&flag=dissertation
Appears in Collection
PH-Theses_Master(석사논문)
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