This paper presents a data-driven fault detection and isolation (FDI) for a multirotor system using Koopman operator and Luenberger observer. Koopman operator is an infinite-dimensional linear operator that can transform nonlinear dynamical systems into linear ones. Using this transformation, our aim is to apply the linear fault detection method to the nonlinear system. Initially, a Koopman operator-based linear model is derived to represent the multirotor system, considering factors like non-diagonal inertial tensor, center of gravity variations, aerodynamic effects, and actuator dynamics. Various candidate lifting functions are evaluated for prediction performance and compared using the root mean square error to identify the most suitable one. Subsequently, a Koopman operator-based Luenberger observer is proposed using the lifted linear model to generate residuals for identifying faulty actuators. Simulation and experimental results demonstrate the effectiveness of the proposed observer in detecting actuator faults such as bias and loss of effectiveness, without the need for an explicitly defined fault dataset.