DC Field | Value | Language |
---|---|---|
dc.contributor.author | Youn, Taesik | ko |
dc.contributor.author | Kim, Taewan | ko |
dc.contributor.author | Han, Sunkyu | ko |
dc.date.accessioned | 2024-09-05T06:00:09Z | - |
dc.date.available | 2024-09-05T06:00:09Z | - |
dc.date.created | 2024-08-29 | - |
dc.date.issued | 2024-06 | - |
dc.identifier.citation | CHEMICAL COMMUNICATIONS, v.60, no.50, pp.6391 - 6394 | - |
dc.identifier.issn | 1359-7345 | - |
dc.identifier.uri | http://hdl.handle.net/10203/322636 | - |
dc.description.abstract | In this study, we present the first total synthesis of (-)-securingine G. Diverging from the proposed biosynthetic pathway, our approach involves the addition of nucleophilic pyridine anion species to the electrophilic menisdaurilide congener. Crucially, incorporating a weakly basic yet nucleophilic tri(2-pyridinyl)lanthanum complex proved essential to circumvent undesired base-mediated pathways during the key coupling reaction. Notably, we introduce n-Bu3La<middle dot>5LiCl as a new exchange reagent, facilitating efficient halide/lanthanum exchange of (hetero)aryl halides. In this study, we present the first total synthesis of (-)-securingine G. | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Total synthesis of (-)-securingine G | - |
dc.type | Article | - |
dc.identifier.wosid | 001237479600001 | - |
dc.identifier.scopusid | 2-s2.0-85195042832 | - |
dc.type.rims | ART | - |
dc.citation.volume | 60 | - |
dc.citation.issue | 50 | - |
dc.citation.beginningpage | 6391 | - |
dc.citation.endingpage | 6394 | - |
dc.citation.publicationname | CHEMICAL COMMUNICATIONS | - |
dc.identifier.doi | 10.1039/d4cc01075b | - |
dc.contributor.localauthor | Han, Sunkyu | - |
dc.contributor.nonIdAuthor | Youn, Taesik | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | DEPROTECTION | - |
dc.subject.keywordPlus | BENZYLATION | - |
dc.subject.keywordPlus | ACETALS | - |
dc.subject.keywordPlus | MILD | - |
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