Estimation of Aortic Pressure Waveform via Dynamic System Modeling between Aortic Pressure and Cuff Oscillometric Signal

Abstract

Arterial stiffness is a crucial indicator in assessing cardiovascular health and determining vascular age. The augmentation index, which is obtained from aortic pressure wave analysis, is a reliable indicator of overall vascular stiffness. In this study, we use a dynamic system to model the relationship between cuff pressure and aortic pressure to obtain arterial pressure waveforms non-invasively. Using a cardiovascular simulator and upper-arm phantom, we recreate blood-pressure measurements using a cuff. Simultaneously measuring aortic and cuff pressures allows us to calculate their transfer function. By utilizing this transfer function from the cuff'’s oscillometric signal under pressure, we confirmed the feasibility of non-invasively estimating the aortic pressure waveform.