DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 최명철 | - |
dc.contributor.author | Lee, Jaehee | - |
dc.contributor.author | 이재희 | - |
dc.date.accessioned | 2024-08-08T19:31:07Z | - |
dc.date.available | 2024-08-08T19:31:07Z | - |
dc.date.issued | 2024 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=1099236&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/322024 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 바이오및뇌공학과, 2024.2,[iii, 53 p. :] | - |
dc.description.abstract | Lipid vesicles are self-assembled structures composed of lipid bilayers that surround water or cellular cytoplasm. The electric double layers around lipid vesicles play crucial roles in various fields, such as artificial cells and drug delivery systems. While previous studies have reported the controllable adsorption of ions onto the membrane surfaces depending on the lipid composition, systematic researches on the overall structure of the electric double layer, including ion distributions and effective surface charges, have been lacking. In this dissertation, we measure the second virial coefficient (B$_2$) of lipid vesicles using optical bottle technique and subsequently profile the characteristics of the electric double layer, including charge reconstruction factors and Debye length. In particular, we demonstrate that the involvement of water-derived H$^+$ ions is a significant factor influencing charge regulation, and the presence of DOPC around DOPG can induce giant charge reconstruction of the lipid vesicles by altering the topological structure of the stabilization shell for adsorbed cations. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | 지질 소포▼a전기 이중층▼a전하 재구축▼a안정화 껍질▼a2차 비리얼 계수▼a광학 병 | - |
dc.subject | Lipid vesicle▼aElectric double layer▼aCharge reconstruction▼aStabilization shell▼aThe second virial coefficient▼aOptical bottle | - |
dc.title | Study of giant charge reconstruction on lipid vesicles using optical bottle technique | - |
dc.title.alternative | 광학 병 기술을 이용한 지질 소포 상에서의 대규모 전하 재구축에 대한 연구 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :바이오및뇌공학과, | - |
dc.contributor.alternativeauthor | Choi, Myung Chul | - |
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