DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 정기훈 | - |
dc.contributor.author | Lee, Sejin | - |
dc.contributor.author | 이세진 | - |
dc.date.accessioned | 2024-07-25T19:30:58Z | - |
dc.date.available | 2024-07-25T19:30:58Z | - |
dc.date.issued | 2023 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=1045787&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/320599 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 바이오및뇌공학과, 2023.8,[iv, 47 p. :] | - |
dc.description.abstract | Breath biopsy is a non-invasive method for detecting various biomarkers present in respiratory droplets. Conventional techniques like PCR and gas chromatography-mass spectrometry have drawbacks such as long measurement times and complexity. Surface-enhanced Raman spectroscopy (SERS) offers high sensitivity and selectivity, making it suitable for breath aerosol biomarker detection. However, the high velocity and small volume of breath aerosols often cause rebounding from SERS substrates, reducing collection efficiency. To address this, we developed TEOS-coated nanocomposite SERS substrates to enhance breath aerosol sample adsorption. The substrates were fabricated by thermally dewetting a thin Au film, and TEOS was coated using plasma-enhanced chemical vapor deposition (PECVD) technology. The porous nature of the TEOS coating physically entraps aerosols, leading to efficient capture. This innovative approach enables rapid collection and high aerosol concentration for SERS analysis of breath samples. By improving sample collection efficiency, our method enhances the potential of SERS for breath analysis in clinical applications. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | 표면증강라만산란▼a나노복합체▼a호기 생검 | - |
dc.subject | SERS▼aBreath Biopsy▼aTEOS▼aNanocomposite | - |
dc.title | TEOS-coated nanocomposite SERS substrate for breath biomarker detection | - |
dc.title.alternative | TEOS-금나노섬 표면증강라만산란 기판을 사용한 호기 비말 내 바이오마커 탐지 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :바이오및뇌공학과, | - |
dc.contributor.alternativeauthor | Jeong, Ki-Hun | - |
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