DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Lee, Jie-Oh | - |
dc.contributor.advisor | 이지오 | - |
dc.contributor.author | Kim, Young-Jin | - |
dc.contributor.author | 김영진 | - |
dc.date.accessioned | 2011-12-13T04:50:03Z | - |
dc.date.available | 2011-12-13T04:50:03Z | - |
dc.date.issued | 2005 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=243570&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/32006 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 화학과, 2005.2, [ iv, 51 p. ] | - |
dc.description.abstract | Lipopolysaccharide binding protein (LBP) is a 60 kDa acute phase glycoprotein capable of binding to LPS of Gram-negative bacteria and facilitating its interaction with cellular receptors. This process is thought to be of great importance in systemic inflammatory reactions such as septic shock. To study molecular basis of LPS binding and transfer by LBP, we overproduced and purified LBP in Hi5 insect cells using recombinant baculoviruses. The purified LBP was crystallized by vapor diffusion technique. The LBP crystals diffracted x-ray to 2.8Å resolution and the structure determination is under progress. The crystal structure of LBP will be used as a key of drug for use in the treatment of Gram-negative bacterial sepsis. | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Fluorene | - |
dc.subject | Organic Field Effect Transistor | - |
dc.subject | LBP 와 Tollht-Emitting Diode | - |
dc.subject | Selenopheneture absorption | - |
dc.subject | 전단시험 | - |
dc.subject | 셀레노펜쳬 압축시험 | - |
dc.subject | 플루오렌 | - |
dc.subject | LBP and TollNA 유기 전계 효과 트랜지스터 | - |
dc.subject | pull-off test | - |
dc.title | crystallization of LPS receptors, LBP and Toll | - |
dc.title.alternative | LPS 수용체 LBP와 Toll 결정화에 관한 연구 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 243570/325007 | - |
dc.description.department | 한국과학기술원 : 화학과, | - |
dc.identifier.uid | 020033122 | - |
dc.contributor.localauthor | Lee, Jie-Oh | - |
dc.contributor.localauthor | 이지오 | - |
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