DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, Jae-Byum | ko |
dc.contributor.author | Yoon, Young-Gyu | ko |
dc.contributor.author | Seo, Junyoung | ko |
dc.contributor.author | Sim, Yeonbo | ko |
dc.contributor.author | Kim, Jee Won | ko |
dc.date.accessioned | 2024-05-30T07:00:27Z | - |
dc.date.available | 2024-05-30T07:00:27Z | - |
dc.identifier.uri | http://hdl.handle.net/10203/319564 | - |
dc.description.abstract | The present disclosure provides a method and apparatus for biomolecular multiplexed imaging through the iterative unmixing of fluorophores. According to the first embodiments of the present disclosure, although signals of two fluorophores are detected in the first fluorescent detection spectral range, the signals of the two images obtained from two detection spectral ranges can be unmixed through the iterative minimization of mutual information. Furthermore, the present disclosure provides a multi-color unmixing method and apparatus through the iterative minimization of mutual information. In the second embodiments of the present disclosure, a plurality of images of a plurality of fluorophores marking different biomolecules, respectively, for example, N fluorophores are obtained. Images, each containing the signals of single fluorophore can be obatined from the obtained images while minimizing the mutual information shared by images of each of pairs each consisting of two of the obtained images. | - |
dc.title | METHOD AND APPARATUS FOR MULTIPLEXED IMAGING OF BIOMOLECULE THROUGH ITERATIVE UNMIXING OF FLUOROPHORE SIGNALS | - |
dc.title.alternative | 형광단 신호의 반복적 미혼합을 통한 생체 분자의 다중화된 이미징을 위한 방법과 장치 | - |
dc.type | Patent | - |
dc.type.rims | PAT | - |
dc.contributor.localauthor | Chang, Jae-Byum | - |
dc.contributor.nonIdAuthor | Yoon, Young-Gyu | - |
dc.contributor.nonIdAuthor | Seo, Junyoung | - |
dc.contributor.nonIdAuthor | Sim, Yeonbo | - |
dc.contributor.nonIdAuthor | Kim, Jee Won | - |
dc.contributor.assignee | KAIST | - |
dc.identifier.iprsType | 특허 | - |
dc.identifier.patentApplicationNumber | 17445629 | - |
dc.identifier.patentRegistrationNumber | 11988606 | - |
dc.date.application | 2021-08-23 | - |
dc.date.registration | 2024-05-21 | - |
dc.publisher.country | US | - |
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