Microfluidic elisa system for the diagnosis of hepatitis b using microwells made of anodic aluminum oxide

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An efficient microfluidic system for diagnosing disease marker molecules is reported. This system is constructed with the anodic aluminum oxide (AAO) as a porous substrate, which provides havens for target proteins and their antibodies from shear force of flow. AAO is embedded on microfluidic channels, where hepatitis B virus (HBV) antibody is immobilized in the surface-modified AAO pores. The performance using porous AAO in a PDMS microfluidic device is comparable to that of conventional ELISA system for the detection of hepatitis B surface antigen (HBsAg).
Publisher
Chemical and Biological Microsystems Society
Issue Date
2007-10
Language
English
Citation

11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, pp.1261 - 1263

URI
http://hdl.handle.net/10203/316808
Appears in Collection
CBE-Conference Papers(학술회의논문)
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