DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Kyeong Hwan | ko |
dc.contributor.author | Singha, Subhankar | ko |
dc.contributor.author | Jun, Yong Woong | ko |
dc.contributor.author | Reo, Ye Jin | ko |
dc.contributor.author | Kim, Hye Rim | ko |
dc.contributor.author | Ryu, Hye Gun | ko |
dc.contributor.author | Bhunia, Snehasis | ko |
dc.contributor.author | Ahn, Kyo Han | ko |
dc.date.accessioned | 2023-05-03T07:01:15Z | - |
dc.date.available | 2023-05-03T07:01:15Z | - |
dc.date.created | 2023-05-03 | - |
dc.date.created | 2023-05-03 | - |
dc.date.created | 2023-05-03 | - |
dc.date.issued | 2019-10 | - |
dc.identifier.citation | CHEMICAL SCIENCE, v.10, no.39, pp.9028 - 9037 | - |
dc.identifier.issn | 2041-6520 | - |
dc.identifier.uri | http://hdl.handle.net/10203/306517 | - |
dc.description.abstract | Organic fluorophores emitting in the far-red/near-infrared (NIR) wavelength region are in great demand for minimal autofluorescence and reduced light scattering in deep tissue or whole body imaging. Currently, only a few classes of far-red/NIR fluorophores are available including widely used cyanine dyes, which are susceptible to photobleaching and form nonfluorescent aggregates. Even rare are those far-red/NIR emitting dyes that have two-photon imaging capability. Here we report a new class of far-red/NIR-emitting dyes that are photo-stable, very bright, biocompatible, and also two-photon absorbing. The introduction of an electron-withdrawing group such as N-acyl or N-alkoxycarbonyl groups on the C-10-amino substituent of the new julolidine-derived amino-Si-pyronin dyes (ASiP(j)), which emit in the far-red region, causes large bathochromic shifts, leading to NIR-emitting amino-Si-pyronin dyes (NIR-ASiP(j)) having high cellular stability. Furthermore, the ASiP(j)-NIR-ASiP(j) couple offers a novel ratiometric bioimaging platform with a large spectral gap, as demonstrated here with a boronate-containing NIR-ASiP(j) derivative that is converted to the corresponding ASiP(j) dye upon reaction with hydrogen peroxide. | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Far-red/near-infrared emitting, two-photon absorbing, and bio-stable amino-Si-pyronin dyes | - |
dc.type | Article | - |
dc.identifier.wosid | 000489761300011 | - |
dc.identifier.scopusid | 2-s2.0-85073452703 | - |
dc.type.rims | ART | - |
dc.citation.volume | 10 | - |
dc.citation.issue | 39 | - |
dc.citation.beginningpage | 9028 | - |
dc.citation.endingpage | 9037 | - |
dc.citation.publicationname | CHEMICAL SCIENCE | - |
dc.identifier.doi | 10.1039/c9sc02287b | - |
dc.contributor.localauthor | Jun, Yong Woong | - |
dc.contributor.nonIdAuthor | Kim, Kyeong Hwan | - |
dc.contributor.nonIdAuthor | Singha, Subhankar | - |
dc.contributor.nonIdAuthor | Reo, Ye Jin | - |
dc.contributor.nonIdAuthor | Kim, Hye Rim | - |
dc.contributor.nonIdAuthor | Ryu, Hye Gun | - |
dc.contributor.nonIdAuthor | Bhunia, Snehasis | - |
dc.contributor.nonIdAuthor | Ahn, Kyo Han | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | SUBSTITUTED XANTHENE DYES | - |
dc.subject.keywordPlus | FLUORESCENT DYES | - |
dc.subject.keywordPlus | RATIONAL DESIGN | - |
dc.subject.keywordPlus | PROBES | - |
dc.subject.keywordPlus | RHODAMINE | - |
dc.subject.keywordPlus | FLUOROPHORE | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | STRATEGY | - |
dc.subject.keywordPlus | ANALOGS | - |
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