A fluorescent hydrazone exchange probe of pyridoxal phosphate for the assessment of vitamin B6 status

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dc.contributor.authorJun, Yong Woongko
dc.contributor.authorHebenbrock, Marianko
dc.contributor.authorKool, Eric T.ko
dc.date.accessioned2023-05-03T07:01:02Z-
dc.date.available2023-05-03T07:01:02Z-
dc.date.created2023-05-03-
dc.date.created2023-05-03-
dc.date.created2023-05-03-
dc.date.issued2020-01-
dc.identifier.citationCHEMICAL COMMUNICATIONS, v.56, no.2, pp.317 - 320-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10203/306514-
dc.description.abstractAbnormal vitamin B6 status, marked by deficient intracellular concentrations of pyridoxal phosphate (PLP), is classified as a direct biomarker based on its biomedical significance. However, there exist no direct methods for measuring vitamin B6 status in intact cells. Here we describe the development of a fluorogenic probe, RAB6, which shows remarkable selectivity for PLP among the B6 vitamers and other cellular aldehydes.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleA fluorescent hydrazone exchange probe of pyridoxal phosphate for the assessment of vitamin B6 status-
dc.typeArticle-
dc.identifier.wosid000503765300028-
dc.identifier.scopusid2-s2.0-85076991239-
dc.type.rimsART-
dc.citation.volume56-
dc.citation.issue2-
dc.citation.beginningpage317-
dc.citation.endingpage320-
dc.citation.publicationnameCHEMICAL COMMUNICATIONS-
dc.identifier.doi10.1039/c9cc08458d-
dc.contributor.localauthorJun, Yong Woong-
dc.contributor.nonIdAuthorHebenbrock, Marian-
dc.contributor.nonIdAuthorKool, Eric T.-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusBIOSYNTHESIS-
dc.subject.keywordPlusSURVIVAL-
dc.subject.keywordPlusTISSUE-
dc.subject.keywordPlusKINASE-
dc.subject.keywordPlusDIET-
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