DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dai, Mingchong | ko |
dc.contributor.author | Lee, Hyori | ko |
dc.contributor.author | Yang, Yun Jae | ko |
dc.contributor.author | Santra, Mithun | ko |
dc.contributor.author | Song, Chang Wook | ko |
dc.contributor.author | Jun, Yong Woong | ko |
dc.contributor.author | Reo, Ye Jin | ko |
dc.contributor.author | Kim, Won Jong | ko |
dc.contributor.author | Ahn, Kyo Han | ko |
dc.date.accessioned | 2023-05-03T07:00:41Z | - |
dc.date.available | 2023-05-03T07:00:41Z | - |
dc.date.created | 2023-05-03 | - |
dc.date.created | 2023-05-03 | - |
dc.date.created | 2023-05-03 | - |
dc.date.issued | 2020-09 | - |
dc.identifier.citation | CHEMISTRY-A EUROPEAN JOURNAL, v.26, no.50, pp.11549 - 11557 | - |
dc.identifier.issn | 0947-6539 | - |
dc.identifier.uri | http://hdl.handle.net/10203/306509 | - |
dc.description.abstract | Photostable and near-infrared (NIR)-emitting organic fluorophores with large Stokes shifts are in great demand for long-term bioimaging at deeper depths with minimal autofluorescence and self-quenching. Herein, a new class of benzorhodamines and their analogues that are photostable and emit in the NIR region (up to 785 nm) with large Stokes shifts (>120 nm) is reported. The synthesis involves condensation of 7-alkylamino-2-naphthols with 2-[4-(dimethylamino)-2-hydroxybenzoyl]benzoic acid, which leads to bent-shaped benzorhodamines that emit orange fluorescence (approximate to 600 nm); however, introduction of steric hindrance near the condensation site switched the regioselectivity, to provide a linear benzorhodamine system for the first time. The linear benzorhodamine derivatives provide bright fluorescence images in cells and in tissue. A carboxy-benzorhodamine was applied for photothermal therapy of cancer cells and xenograft cancer mice. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Synthesis of Near-Infrared-Emitting Benzorhodamines and Their Applications to Bioimaging and Photothermal Therapy | - |
dc.type | Article | - |
dc.identifier.wosid | 000559834000001 | - |
dc.identifier.scopusid | 2-s2.0-85087978988 | - |
dc.type.rims | ART | - |
dc.citation.volume | 26 | - |
dc.citation.issue | 50 | - |
dc.citation.beginningpage | 11549 | - |
dc.citation.endingpage | 11557 | - |
dc.citation.publicationname | CHEMISTRY-A EUROPEAN JOURNAL | - |
dc.identifier.doi | 10.1002/chem.202001163 | - |
dc.contributor.localauthor | Jun, Yong Woong | - |
dc.contributor.nonIdAuthor | Dai, Mingchong | - |
dc.contributor.nonIdAuthor | Lee, Hyori | - |
dc.contributor.nonIdAuthor | Yang, Yun Jae | - |
dc.contributor.nonIdAuthor | Santra, Mithun | - |
dc.contributor.nonIdAuthor | Song, Chang Wook | - |
dc.contributor.nonIdAuthor | Reo, Ye Jin | - |
dc.contributor.nonIdAuthor | Kim, Won Jong | - |
dc.contributor.nonIdAuthor | Ahn, Kyo Han | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | benzorhodamines | - |
dc.subject.keywordAuthor | dyes | - |
dc.subject.keywordAuthor | pigments | - |
dc.subject.keywordAuthor | fluorescence | - |
dc.subject.keywordAuthor | imaging agents | - |
dc.subject.keywordAuthor | photothermal therapy | - |
dc.subject.keywordPlus | RATIONAL DESIGN | - |
dc.subject.keywordPlus | FLUORESCENCE | - |
dc.subject.keywordPlus | DYES | - |
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