DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hwangbo, Yul | ko |
dc.contributor.author | Kim, Jung Min | ko |
dc.contributor.author | Park, Young Joo | ko |
dc.contributor.author | Lee, Eun Kyung | ko |
dc.contributor.author | Lee, You Jin | ko |
dc.contributor.author | Park, Do Joon | ko |
dc.contributor.author | Choi, Young Sik | ko |
dc.contributor.author | Lee, Kang Dae | ko |
dc.contributor.author | Sohn, Seo Young | ko |
dc.contributor.author | Kim, Sun Wook | ko |
dc.contributor.author | Chung, Jae Hoon | ko |
dc.contributor.author | Lim, Dong Jun | ko |
dc.contributor.author | Kim, Min Hee | ko |
dc.contributor.author | Kim, Min Joo | ko |
dc.contributor.author | Jo, Young Suk | ko |
dc.contributor.author | Shong, Min Ho | ko |
dc.contributor.author | Koong, Sung-Soo | ko |
dc.contributor.author | Hahm, Jong Ryeal | ko |
dc.contributor.author | Jung, Jung Hwa | ko |
dc.contributor.author | Yi, Ka Hee | ko |
dc.date.accessioned | 2023-04-12T06:00:40Z | - |
dc.date.available | 2023-04-12T06:00:40Z | - |
dc.date.created | 2023-04-12 | - |
dc.date.created | 2023-04-12 | - |
dc.date.created | 2023-04-12 | - |
dc.date.issued | 2017-02 | - |
dc.identifier.citation | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, v.102, no.2, pp.625 - 633 | - |
dc.identifier.issn | 0021-972X | - |
dc.identifier.uri | http://hdl.handle.net/10203/306133 | - |
dc.description.abstract | Context: Small papillary thyroid cancer (PTC) generally has an excellent prognosis. However, long-term recurrence is not uncommon and sometimes leads to morbidity or mortality. Objective: To identify high-risk factors for long-term recurrence in patients with small PTC by stratifying their pathologic characteristics. Design, Setting, and Patients: We conducted a nationwide, retrospective, multicenter study of 3282 patients with PTC sized <= 2 cm from 9 high-volume hospitals in Korea. Main Outcome Measures: The maximally selected x(2) method was used to find the best cutoff points of tumor size, the number of metastatic lymph nodes (LNs), and the ratio of metastatic/examined LNs (LNR) to predict recurrence. Kaplan-Meier analysis and the Cox proportional hazards regression model were used to analyze recurrence and risk factors. Results: The optimal tumor size cutoff was 1.8 cm (10-year recurrence rates for tumors sized 0.1 to 1.7 cm and 1.8 to 2.0 cm: 7.7% vs 17.2%, respectively). Metastatic LNs <= 1 and >= 2 provided optimal estimates of recurrence (10-year recurrence rates: 4.0% vs 16.8%, respectively). The LNR of 0.19 was the optimal cutoff point for predicting the risk of recurrence (10-year recurrence rates for LNRs of 0 to 0.18 and 0.19 to 1: 2.7% vs 16.2%, respectively). LN metastasis, lobectomy, tumor size >= 1.8 cm, and bilateral tumors were independent risk factors for recurrence. Conclusions: Long-term recurrence was increased in patients who underwent lobectomy or with tumor sized >= 1.8 cm, 2 or more metastatic LNs, or bilateral tumors. For patients with these high-risk features, total thyroidectomy could be considered to avoid reoperation. | - |
dc.language | English | - |
dc.publisher | ENDOCRINE SOC | - |
dc.title | Long-Term Recurrence of Small Papillary Thyroid Cancer and Its Risk Factors in a Korean Multicenter Study | - |
dc.type | Article | - |
dc.identifier.wosid | 000397240900035 | - |
dc.identifier.scopusid | 2-s2.0-85012075590 | - |
dc.type.rims | ART | - |
dc.citation.volume | 102 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 625 | - |
dc.citation.endingpage | 633 | - |
dc.citation.publicationname | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | - |
dc.identifier.doi | 10.1210/jc.2016-2287 | - |
dc.contributor.localauthor | Shong, Min Ho | - |
dc.contributor.nonIdAuthor | Hwangbo, Yul | - |
dc.contributor.nonIdAuthor | Kim, Jung Min | - |
dc.contributor.nonIdAuthor | Park, Young Joo | - |
dc.contributor.nonIdAuthor | Lee, Eun Kyung | - |
dc.contributor.nonIdAuthor | Lee, You Jin | - |
dc.contributor.nonIdAuthor | Park, Do Joon | - |
dc.contributor.nonIdAuthor | Choi, Young Sik | - |
dc.contributor.nonIdAuthor | Lee, Kang Dae | - |
dc.contributor.nonIdAuthor | Sohn, Seo Young | - |
dc.contributor.nonIdAuthor | Kim, Sun Wook | - |
dc.contributor.nonIdAuthor | Chung, Jae Hoon | - |
dc.contributor.nonIdAuthor | Lim, Dong Jun | - |
dc.contributor.nonIdAuthor | Kim, Min Hee | - |
dc.contributor.nonIdAuthor | Kim, Min Joo | - |
dc.contributor.nonIdAuthor | Jo, Young Suk | - |
dc.contributor.nonIdAuthor | Koong, Sung-Soo | - |
dc.contributor.nonIdAuthor | Hahm, Jong Ryeal | - |
dc.contributor.nonIdAuthor | Jung, Jung Hwa | - |
dc.contributor.nonIdAuthor | Yi, Ka Hee | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | LYMPH-NODE METASTASES | - |
dc.subject.keywordPlus | RETROSPECTIVE ANALYSIS | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | MICROCARCINOMA | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | MULTIFOCALITY | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | IMPACT | - |
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