DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이균민 | ko |
dc.contributor.author | 김노수 | ko |
dc.date.accessioned | 2022-12-21T00:00:13Z | - |
dc.date.available | 2022-12-21T00:00:13Z | - |
dc.identifier.uri | http://hdl.handle.net/10203/303383 | - |
dc.description.abstract | The present invention relates to an antisense nucleotide of caspase-3, an expression vector encoding antisense RNA of caspase-3, and an inhibition method of cellular apoptosis in recombinant Chinese hamster ovary (CHO) cells using the same. More precisely, the present invention relates to an antisense nucleotide composed of a base sequence represented by Sequence ID No. 1, which suppresses the expression of caspase-3, an expression vector containing the above antisense nucleotide and expressing antisense RNA of caspase-3, and an inhibition method of apoptosis of recombinant cells by suppressing the expression of caspase-3 through introducing the above expression vector into the recombinant cells and then expressing antisense RNA of caspase-3. According to the present invention, apoptosis can be inhibited by suppressing the activation of caspase-3, which is related to the apoptosis, and the integrity of target protein produced in the recombinant cells can be enhanced. | - |
dc.title | Inhibition of apoptosis by the expression of antisenseRNA of caspase-3 | - |
dc.title.alternative | 카스파제-3의 안티센스 rna 발현에 의한 세포 사멸 억제 | - |
dc.type | Patent | - |
dc.type.rims | PAT | - |
dc.contributor.localauthor | 이균민 | - |
dc.contributor.nonIdAuthor | 김노수 | - |
dc.contributor.assignee | KAIST | - |
dc.identifier.iprsType | 특허 | - |
dc.identifier.patentApplicationNumber | 02020798.1 | - |
dc.identifier.patentRegistrationNumber | 1293563 | - |
dc.date.application | 2002-09-17 | - |
dc.date.registration | 2005-12-27 | - |
dc.publisher.country | GE | - |
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