Potential Link Between Cognition and Motor Reserve in Patients With Parkinson’s DiseasePotential Link Between Cognition and Motor Reserve in Patients With Parkinson’s Disease
A total of 163 patients with drug-naïve PD who underwent 18F-FP-CIT PET, brain MRI, and a detailed neuropsychological test were enrolled. We estimated individual motor reserve based on initial motor deficits and striatal dopamine depletion using a residual model. We performed correlation analyses between motor reserve estimates and cognitive composite scores.