In this paper, a boost-oriented single-inductor dual-output (BO-SIDO) step-up/down DC-DC converter is presented. The BO-SIDO design enables only 1×RON conduction in all inductor-current paths, improving power efficiency. While regulating the heavy-loaded boost output, the seamless buck conversion can be embedded adaptively to the buck load. The chip was fabricated in 0.5-m CMOS, and it achieved 96.6% peak efficiency and maximum output power of 5.6W.