C–H activation

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Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform for molecular syntheses, enabling applications to natural product syntheses, late-stage modification, pharmaceutical industries and material sciences, among others. This Primer summarizes representative best practices for the experimental set-up and data deposition for C–H activation, as well as discussing key developments including recent advances in asymmetric, photoinduced and electrocatalytic C–H activation. Likewise, strategies for applications of C–H activation towards the assembly of structurally complex (bio)polymers and drugs in academia and industry are discussed. In addition, current limitations in C–H activation and possible approaches for overcoming these shortcomings are reviewed.
Publisher
Springer Nature
Issue Date
2021-12
Language
English
Citation

Nature Reviews Methods Primers, v.1, no.1

ISSN
2662-8449
DOI
10.1038/s43586-021-00041-2
URI
http://hdl.handle.net/10203/296827
Appears in Collection
CH-Journal Papers(저널논문)
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