DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ganesan, Vinothkumar | ko |
dc.contributor.author | Kim, Jennifer Juhyun | ko |
dc.contributor.author | Shin, Jeongcheol | ko |
dc.contributor.author | Park, Kiyoung | ko |
dc.contributor.author | Yoon, Sungho | ko |
dc.date.accessioned | 2022-05-24T06:02:07Z | - |
dc.date.available | 2022-05-24T06:02:07Z | - |
dc.date.created | 2022-05-24 | - |
dc.date.created | 2022-05-24 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.citation | INORGANIC CHEMISTRY, v.61, no.15, pp.5683 - 5690 | - |
dc.identifier.issn | 0020-1669 | - |
dc.identifier.uri | http://hdl.handle.net/10203/296664 | - |
dc.description.abstract | Regeneration of nicotinamide adenine dinucleotide(NADH) has been the primary interest in thefield of enzymatictransformation, especially associating oxidoreductases given thestoichiometric consumption. The synthesized carbene-ligatedrhodium complex [(eta 5-Cp*)Rh(MDI)Cl]+[Cp*= pentamethyl-cyclopentadienyl; MDI = 1,1 '-methylenebis(3,3 '-dimethylimidazo-lium)] acts as an exceptional catalyst in the reduction of NAD+toNADH with a turnover frequency of 1730 h-1, which is over twicethat of the higher catalytic activity of the commercially availablecatalyst [Cp*Rh(bpy)Cl]+(bpy = 2,2'-bipyridine). Offsetting thecontentious atmosphere currently taking place over the specificintermediate of the NADH regeneration, this study presentspivotal evidence of a metal hydride intermediate with abis(carbene) ligand: a stable form of the rhodium hydride intermediate, [(eta 5-Cp*)Rh(MDI)H]+, was isolated and fullycharacterized. This enables thorough insight into the possible mechanism and exact intermediate structure in the NAD+reductionprocess | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Efficient Nicotinamide Adenine Dinucleotide Regeneration with aRhodium-Carbene Catalyst and Isolation of a Hydride Intermediate br | - |
dc.type | Article | - |
dc.identifier.wosid | 000791949700001 | - |
dc.identifier.scopusid | 2-s2.0-85128488024 | - |
dc.type.rims | ART | - |
dc.citation.volume | 61 | - |
dc.citation.issue | 15 | - |
dc.citation.beginningpage | 5683 | - |
dc.citation.endingpage | 5690 | - |
dc.citation.publicationname | INORGANIC CHEMISTRY | - |
dc.identifier.doi | 10.1021/acs.inorgchem.2c00059 | - |
dc.contributor.localauthor | Park, Kiyoung | - |
dc.contributor.nonIdAuthor | Ganesan, Vinothkumar | - |
dc.contributor.nonIdAuthor | Kim, Jennifer Juhyun | - |
dc.contributor.nonIdAuthor | Yoon, Sungho | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | BIOORGANOMETALLIC CHEMISTRY | - |
dc.subject.keywordPlus | REGIOSELECTIVE REDUCTION | - |
dc.subject.keywordPlus | RHODIUM(III) COMPLEXES | - |
dc.subject.keywordPlus | NAD(P)-DEPENDENT OXIDOREDUCTASES | - |
dc.subject.keywordPlus | ENANTIOSELECTIVE REDUCTION | - |
dc.subject.keywordPlus | ELECTROCHEMICAL PROPERTIES | - |
dc.subject.keywordPlus | POTENTIAL APPLICATIONS | - |
dc.subject.keywordPlus | MECHANISTIC ASPECTS | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURES | - |
dc.subject.keywordPlus | NADH REGENERATION | - |
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