Engineering Brain Organoids: Toward Mature Neural Circuitry with an Intact Cytoarchitecture

Cited 1 time in webofscience Cited 0 time in scopus
  • Hit : 79
  • Download : 0
DC FieldValueLanguage
dc.contributor.authorJang, Hyunsooko
dc.contributor.authorKim, Seo Hyunko
dc.contributor.authorKoh, Youminko
dc.contributor.authorYoon, Ki-Junko
dc.date.accessioned2022-04-15T06:40:41Z-
dc.date.available2022-04-15T06:40:41Z-
dc.date.created2022-04-04-
dc.date.created2022-04-04-
dc.date.created2022-04-04-
dc.date.issued2022-02-
dc.identifier.citationINTERNATIONAL JOURNAL OF STEM CELLS, v.15, no.1, pp.41 - 59-
dc.identifier.issn2005-3606-
dc.identifier.urihttp://hdl.handle.net/10203/294732-
dc.description.abstractThe emergence of brain organoids as a model system has been a tremendously exciting development in the field of neuroscience. Brain organoids are a gateway to exploring the intricacies of human-specific neurogenesis that have so far eluded the neuroscience community. Regardless, current culture methods have a long way to go in terms of accuracy and reproducibility. To perfectly mimic the human brain, we need to recapitulate the complex in vivo context of the human fetal brain and achieve mature neural circuitry with an intact cytoarchitecture. In this review, we explore the major challenges facing the current brain organoid systems, potential technical breakthroughs to advance brain organoid techniques up to levels similar to an in vivo human developing brain, and the future prospects of this technology.-
dc.languageEnglish-
dc.publisherKOREAN SOC STEM CELL RESEARCH-
dc.titleEngineering Brain Organoids: Toward Mature Neural Circuitry with an Intact Cytoarchitecture-
dc.typeArticle-
dc.identifier.wosid000767314000005-
dc.identifier.scopusid2-s2.0-85129429128-
dc.type.rimsART-
dc.citation.volume15-
dc.citation.issue1-
dc.citation.beginningpage41-
dc.citation.endingpage59-
dc.citation.publicationnameINTERNATIONAL JOURNAL OF STEM CELLS-
dc.identifier.doi10.15283/ijsc22004-
dc.contributor.localauthorYoon, Ki-Jun-
dc.contributor.nonIdAuthorKoh, Youmin-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordAuthorBrain organoid-
dc.subject.keywordAuthorPluripotent stem cell-
dc.subject.keywordAuthorBioengineering-
dc.subject.keywordAuthorMulti-regional identity-
dc.subject.keywordAuthor3-dimensional culture-
dc.subject.keywordPlusPLURIPOTENT STEM-CELLS-
dc.subject.keywordPlusHUMAN CORTICAL ORGANOIDS-
dc.subject.keywordPlusCEREBRAL ORGANOIDS-
dc.subject.keywordPlusEXTRACELLULAR-MATRIX-
dc.subject.keywordPlusRETINAL ORGANOIDS-
dc.subject.keywordPlusSELF-ORGANIZATION-
dc.subject.keywordPlusCHOROID-PLEXUS-
dc.subject.keywordPlusLINEAGE-
dc.subject.keywordPlusGENERATION-
dc.subject.keywordPlusNEURONS-
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 1 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0